نتایج جستجو برای: مدل gep

تعداد نتایج: 121158  

2010
Vanja Zjačić-Rotkvić Maja Berković

Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) are a rare and heterogeneous group of tumors arising from the cells of diffuse endocrine system (DES) scattered through the mucosa of the gastrointestinal tract and pancreas. Tumors were historically termed carcinoid-«cancer-like» due to better prognosis than adenocarcinoma. Yearly incidence of GEP-NETs is estimated to be 1-2 of 100.000 po...

سابقه و هدف: با توجه به اهمیت مسائل کیفیت آب و شرایط زیست‌‌‌محیطی، دمای آب رودخانه‌ها از دو جنبۀ اقتصادی و زیست‌محیطی دارای اهمیت می‌باشد. این پارامتر تأثیر مستقیمی بر تمامی پارامترهای کیفیت آب داشته و نقش مهمی را در زندگی و زیستگاه آبزیان ایفا می‌کند. در نتیجه، با توجه به پیامدهای مهم درجه حرارت برای انجام ارزیابی اثرات زیست‌محیطی و مدیریت مؤثر شیلات، درک وضع حرارتی رودخانه و فرآیندهای تبادل ح...

2017
G. Haripriya

The Generation expansion planning (GEP) problem is a large scale, mixed integer and the most complicated optimization problem. So we are using Multi-objective differential evolution (MODE) for solving the GEP problem. To calculate for best combinations of conventional sources with and without wind farm, GEP problem is considered for test system of and satisfy the constraints by calculating EENS...

Journal: :Asian Pacific journal of cancer prevention : APJCP 2016
Hampig Raphael Kourie Claude Ghorra Marc Rassy Carole Kesserouani Joseph Kattan

BACKGROUND Gastro-entero-pancreatic neuroendocrine neoplasms (GEP-NEN) are relatively rare tumors, not equally distributed in the gastrointestinal system. In 2010, a revised version of the WHO classification of GEP-NENs was published. This study reports for the first time the distribution and characteristics of GEP-NENs in a Lebanese population. MATERIALS AND METHODS This descriptive retrospe...

Journal: :Haematologica 2004
David Grimwade Torsten Haferlach

PURPOSE OF REVIEW This review deals with the emerging promises of gene expression profiling (GEP) and the currently accumulating knowledge about the classification and the discovery of novel disease entities in clinical acute myeloid leukemia (AML). RECENT FINDINGS Gene expression profiling studies in AML have shown that known and novel classes of disease can be recognized by unsupervised ana...

2011
Hee Sung Kim Hye Seung Lee Woo Ho Kim

PURPOSE This study was undertaken to evaluate the significance of cyclooxygenase-2 (COX2) overexpression and the expression of somatostatin receptor (SSTR) subtypes in gastroenteropancreatic neuroendocrine tumors (GEP-NETs). MATERIALS AND METHODS Two hundred and forty-seven cases of GEP-NET, comprising 86 foregut and 156 hindgut primary NETs, and 5 metastatic NETs in the liver, were studied r...

Journal: :Journal of Cancer 2016
Seung Tae Kim Sang Yun Ha Sujin Lee Soomin Ahn Jeeyun Lee Se Hoon Park Joon Oh Park Ho Yeong Lim Won Ki Kang Kyoung-Mee Kim Young Suk Park

Programmed death-ligand 1 (PD-L1), which is expressed on many cancer cells, interacts with PD1 expressed on the surface of T cells, inhibiting the T cells and blocking the antitumor immune response. Expression of PD-L1 in gastroenteropancreatic neuroendocrine tumors (GEP-NETs) has not been studied. We investigated the impact of PD-L1 expression in 32 patients with metastatic GEP-NET. The expres...

2015
Sebastian Kaupp-Roberts Rajaventhan Srirajaskanthan John K. Ramage

Gastroenteropancreatic neuroendocrine tumours (GEP-NETs) have the ability to induce symptoms either by their direct mass effect on local tissues (symptoms such as pain, bowel obstruction, obstructive jaundice, and bleeding), or by the ectopic secretion of bioactive compounds. GEP-NETs are frequently associated with significant diagnostic delays, and metastatic disease is often a feature at init...

2011
Rong Tang Changjie Tang Jie Zuo Ning Yang Kaikuo Xu

The problem of complex network clustering has been long studied and a satisfactory solution is still lack so far. By cohesion superiority of Gene Expression Programming and the information-theoretic topology compression framework, a novel algorithm, CNC-GEP, is proposed for complex network clustering. With no prior knowledge of the number of modules in networks, CNC-GEP not only determines the ...

Journal: :Journal of the National Comprehensive Cancer Network : JNCCN 2014
David S Ettinger Charles R Handorf Mark Agulnik Daniel W Bowles Justin M Cates Mihaela Cristea Efrat Dotan Keith D Eaton Panagiotis M Fidias David Gierada G Weldon Gilcrease Kelly Godby Renuka Iyer Renato Lenzi John Phay Asif Rashid Leonard Saltz Richard B Schwab Lawrence N Shulman Jeffrey B Smerage Marvaretta M Stevenson Gauri R Varadhachary Jonathan S Zager Weining Ken Zhen Mary Anne Bergman Deborah A Freedman-Cass

The NCCN Guidelines for Occult Primary tumors provide recommendations for the evaluation, workup, management, and follow-up of patients with occult primary tumors (cancers of unknown primary). These NCCN Guidelines Insights summarize major discussion points of the 2014 NCCN Occult Primary panel meeting. The panel discussed gene expression profiling (GEP) for the identification of the tissue of ...

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