Recently, Building Information Modeling (BIM) technology has attracted much attention in the Architecture, Engineering, and Construction (AEC) industry. Despite the growing interest in BIM technology, the benefits of BIM have not yet been fully realized during the course of implementation of BIM because of its low adoption rate among architects. Therefore, it is significant important in success...

Building Information Modelling (BIM) is considered an innovation for construction, with the potential to digitise various construction processes. Being an innovation, it affects and is affected by organisational aspects. At the same time, innovations are better observed at a project level. This study connects intraand interorganisational levels mobilised during BIM implementation. To explore th...

Paclitaxel is used to treat breast cancers, but the mechanisms by which it induces apoptosis are poorly understood. Consequently, we have studied the role of the FoxO transcription factors in determining cellular response to paclitaxel. Western blotting revealed that in a panel of nine breast cancer cell lines expression of FoxO1a and FoxO3a correlated with the expression of the pro-apoptotic F...

Considerable amount of research has been developed that investigate the benefits of Building Information Modelling (BIM) for design and construction. However, as suggested in the UK Government Strategy, the relevant gains and difficulties related to the adoption of BIM in the operational stages of the project life cycle are considerably less explored in the available literature. In this respect...

Aberrant changes in the expression of the pro-apoptotic protein, BCL-2-like 11 (BIM), can result in either impaired or excessive apoptosis, which can contribute to tumorigenesis and degenerative disorders, respectively. Altering BIM pre-mRNA splicing is an attractive approach to modulate apoptosis because BIM activity is partly determined by the alternative splicing of exons 3 or 4, whereby exo...

The integration of building information modelling (BIM) and geographic information system (GIS) in construction management is a new and fast developing trend in recent years, from research to industrial practice. BIM has advantages on rich geometric and semantic information through the building life cycle, while GIS is a broad field covering geovisualization-based decision making and geospatial...

The construction industry is always criticized for lack of collaboration and ineffective communication. Building Information Modelling (BIM) is introduced to the industry as a concept that involves a series of changes on organizational processes, tools, structures and policies, as well as the interaction patterns among individuals and professional groups. Proponents claim that BIM will improve ...

Building Information Modeling (BIM) is a process by which a digital representation of the physical and functional characteristics of a facility are built, analyzed, documented and assessed virtually, then revised iteratively until the optimal model is documented. The virtual BIM model is not only graphical design but also a virtual database which includes the management data. So the constructio...

Building Information Modeling (BIM) has proven its value for design in the architecture, engineering, and construction industry. However, currently only a few leading firms succeed in reaping the full potential of BIM. Especially, specialist designers remain excluded from innovative practices. Reasons include the technical hurdles of BIM adoption and a misfit between human agency versus the aff...

The proapoptotic Bcl-2 homolog Bim was shown to control the apoptosis of both T cells and hepatocytes. This dual role of Bim might be particularly relevant for the development of viral hepatitis, in which both the sensitivity of hepatocytes to apoptosis stimuli and the persistence of cytotoxic T cells are essential factors for the outcome of the disease. The relevance of Bim in regulating survi...