Emerging evidence suggests that TLR (Toll-like receptor) 4 and downstream pathways [MAPKs (mitogen-activated protein kinases) and NF-κB (nuclear factor κB)] play an important role in the pathogenesis of insulin resistance. LPS (lipopolysaccharide) and saturated NEFA (non-esterified fatty acids) activate TLR4, and plasma concentrations of these TLR4 ligands are elevated in obesity and Type 2 dia...

An abstract is not available for this content so a preview has been provided. As you have access to content, full PDF via the ‘Save PDF’ action button.

The satellite LARES 2 is designed to test dragging of inertial frames, or frame-dragging, predicted by Einstein’s theory General Relativity, with accuracy a few parts in thousand. For this purpose, besides the typical requirements for space construction, high density alloy must be used. In paper are reported studies performed on nickel alloy, Haynes 242, that considered possible candidate manuf...

WSI-Mitteilungen , Seite 242 -

Prohormone convertases 1 (PC1) and 2 (PC2) are members of a family of subtilisin-like proprotein convertases responsible for proteolytic maturation of a number of different prohormones and proneuropeptides. Although sharing more than 50% homology in their catalytic domains, PC1 and PC2 exhibit differences in substrate specificity and susceptibility to inhibitors. In addition to these difference...

BACKGROUND The current study investigated the analgesic effect of the Toll-like receptor 4 (TLR4) specific antagonist TAK-242 on neuropathic pain in rats and its underlying mechanism. METHODS A total of 132 adult Sprague-Dawley (SD) rats were randomly divided into four groups: the sham operation group, the neuropathic pain model group, the TAK-242 low-dose treatment group, and the TAK-242 hig...

242

Organised Sound / Volume 18 / Special Issue 03 / December 2013, pp 242 254 DOI: 10.1017/S1355771813000216, Published online: 12 November 2013 Link to this article: http://journals.cambridge.org/abstract_S1355771813000216 How to cite this article: Andrea Valle (2013). Making Acoustic Computer Music: The Rumentarium project. Organised Sound, 18, pp 242-254 doi:10.1017/S1355771813000216 Request Pe...