Several studies have shown that transcranial direct current stimulation (tDCS) is able to enhance performances on verbal and visual working memory (WM) tasks. Available evidence points to the right dorsolateral prefrontal cortex (DLPFC) as a critical area in visual WM, but to date direct comparisons of the effects obtained by stimulating the left versus the right DLPFC in the same subject are l...

Prefrontal cortex plays an important role in decision making (DM), supporting choices in the ordinary uncertainty of everyday life. To assess DM in an unpredictable situation, a playing card task, such as the Iowa Gambling Task (IGT), has been proposed. This task is supposed to specifically test emotion-based learning, linked to the integrity of the ventromedial prefrontal cortex (VMPFC). Howev...

Background: Error awareness is essential to maintain an adaptive and goal-directed behavior and is supposed to rely on the activity of the right dorsolateral prefrontal cortex (DLPFC). However, studies employing electrophysiological methods and functional resonance imaging (fMRI) do not allow to establish a causal relationship between error awareness and implicated brain structures. Objective: ...

Objective: Recent studies on treating obsessive compulsive disorder (OCD) have investigated noninvasive brain stimulation techniques such as transcranial direct current stimulation (tDCS) to improve patients’ impaired emotion and cognition. However, such experiments have yielded mixed results, especially with respect to cognition. This study aimed to investigate whethe...

Objective: Previous studies have reported dorsolateral prefrontal cortex (DLPFC) and posterior parietal (PPC) activation during the performance of spatial working memory (SWM), so we decided to investigate the comparison of Transcranial Direct current stimulation (tDCS) effect between these two areas. Methods: Fifty-four healthy right-handed students (27 female, 27 male; age= 24.3±.2 years) w...

CONTEXT Studies have shown patterns of abnormal dorsolateral prefrontal cortex (DLPFC) functional connectivity with other brain areas in schizophrenia and association of these patterns with a putative susceptibility gene (ZNF804A). However, whether these patterns are trait phenomena linked to genetic risk for illness is unclear. OBJECTIVE To test the hypotheses that altered DLPFC connectivity...

Abstract The left dorsolateral prefrontal cortex (dlPFC) is a key region involved in emotion regulation and an effective target for repetitive transcranial magnetic stimulation (rTMS) treatment depression. Evidence shows that the dlPFC connects with amygdala, emotional responses processing, during regulation. Yet, our understanding of causal regulatory role on amygdala minimal. We performed 3 m...