Dermatophytes are keratinophilic fungi that can be pathogenic for humans and animals by infecting the stratum corneum, nails, claws or hair. The first infection step consists of adherence of arthroconidia to the stratum corneum. The mechanisms and the kinetics of adherence have been investigated using different in vitro and ex vivo experimental models, most notably showing the role of a secrete...

Dermatophytes are keratinophilic fungi responsible for benign and common forms of infection worldwide. However, they can lead to rare and severe diseases in immunocompromised patients. Severe forms include extensive and/or invasive dermatophytosis, i.e., deep dermatophytosis and Majocchi's granuloma. They are reported in immunocompromised hosts with primary (autosomal recessive CARD9 deficiency...

Back ground and Objective: Dermatomycosis are caused by attacking keratinophilic fungi to the human’s or animals’ in keratinic layers. In this study the resources of fungal infection pollutions of dermatophytes existing in the soil of Babol Medical University’s Hospitals have been investigated. Materials and Methods: This descriptive cross-sectional study was performed on the soil of Hospital y...

Mastitis, which has multiple and complex aetiology, is a common syndrome among bovines and inflicts enormous losses on livestock owners. The mastitis cases are infectious in nature and are usually caused by bacteria, fungi/yeasts and some algae. An interesting case of protracted clinical mastitis in a Holstein-Fresian cow in its third lactation was encountered, with exclusive involvement of Geo...

BACKGROUND Dermatophytes are filamentous keratinophilic fungi. Trichophyton rubrum is a prevalent infectious agent in tineas and other skin diseases. Drug therapy is considered to be limited in the treatment of such infections, mainly due to low accessibility of the drug to the tissue attacked and development of antifungal resistance in these microorganisms. In this context, Photodynamic Therap...

Dermatophytes are keratinophilic fungi that infect keratinized tissues causing diseases known as dermatophytoses. Dermatophytes are classified in three genera, Epidermophyton, Microsporum, and Trichophyton. This investigation was performed to study the prevalence of dermatomycosis among 640 patients being evaluated at the dermatology clinics at Kasr elainy, El-Husein and Said Galal hospitals in...

Sewage sludge was examined for keratinolytic and keratinophilic fungi by means of a multi-temperature (23, 26, 29, 33, 37 and 45oC) hair baiting method. Results indicate that this method can be a useful tool for determination of the influence of temperature and other factors on fungal composition in sludge and evaluation of health risk posed by fungal pathogens. The use of the method facilitate...

Keratinophilic fungi are natural colonizers of keratinic substrates. Some are keratinolytic and play an important ecological role in decomposing α-keratins, the insoluble fibrous proteins. Because of the tight packing of their polypeptide chains in α-helix structures and their linkage by disulphide bridges, they are poorly biodegradable. Two main forms of attack have been identified: surface er...