نتایج جستجو برای: فاکتور القاکنندۀ هایپوکسی hif

تعداد نتایج: 23880  

The low fault current of high-impedance faults (HIFs) is one of the main challenges for the protection of distribution networks. The inability of conventional overcurrent relays in detecting these faults results in electric arc continuity that it causes the fire hazard and electric shock and poses a serious threat to human life and network equipment. This paper presents ​an HIF detection algori...

This paper presets a method including a combination of the wavelet transform and fuzzy function approximation (FFA) for high impedance fault (HIF) detection in distribution electricity network. Discrete wavelet transform (DWT) has been used in this paper as a tool for signal analysis. With studying different types of mother signals, detail types and feeder signal, the best case is selected. The...

ژورنال: بوم شناسی آبزیان 2016

In this study, the effects of sublethal concentrations of the Endosulfan on gene expression of hypoxia-inducible factor (HIF-1 α, HIF-2 α) and vascular endothelial growth factor (VEGF) in the gill tissue of Persian sturgeon fingerling (Acipenser persicus) were studied. A total of 360 sturgeons (average weight of 2 ± 0.12 g) exposed to concentrations of 10, 20 and 40 micrograms per liter and VEG...

2001
Frederick E. Domann Min Wang

Hypoxiainducible factor 1 (HIF-1) is an important transcription factor that is expressed upon hypoxia. HIF-1 is a heterodimer of HIF-1α subunit and HIF-1β subunit. HIF-1α is unique to HIF-1 whereas HIF-1β is also known as aryl hydrocarbon receptor (AhR) nuclear translocator (ARNT) gene product. HIF-1β can dimerize with AhR to form AhR complex and can also dimerize with HIF-1α to form HIF-1. HIF...

Journal: :Experimental Eye Research 2021

Echinomycin (EKN), an inhibitor of hypoxia-inducible factor (HIF)-1 DNA-binding activity, has been implied as a possible therapeutic agent in ischemic diseases. Here, we assess EKN hypoxia-driven responses vitro using human primary adult retinal pigment epithelium cells (aRPE) and endothelial (hREC), vivo the laser-induced mouse choroidal neovascularization (CNV) model. Effects on hypoxia-media...

ژورنال: ابن سینا 2016

مقدمه: به‌نظر می‌رسد اثر تمرینات ورزشی بر ارتقای عملکرد جسمانی همیشه با تأثیرات مفید بر ارگان‌های داخلی بدن همراه نیست. تاکنون تأثیر تمرینات تناوبی شدید و هایپوکسی پس از آن، بر پارانشیم ریه بررسی نشده است. هدف پژوهش حاضر بررسی تأثیر هایپوکسی مزمن به‌دنبال یک دوره تمرین تناوبی شدید بر میزان التهاب ریه بود. روش بررسی: 24 سر موش صحرائی نر نژاد ویستار (سن 4 هفته، وزن 4±71 گرم) به‌صورت تصادف...

Journal: :journal of ai and data mining 2014
mahdi banejad hassan ijadi

this paper presets a method including a combination of the wavelet transform and fuzzy function approximation (ffa) for high impedance fault (hif) detection in distribution electricity network. discrete wavelet transform (dwt) has been used in this paper as a tool for signal analysis. with studying different types of mother signals, detail types and feeder signal, the best case is selected. the...

ژورنال: ارمغان دانش 2019

Background and Aim: Type 2 diabetes exerts oxidative and anti-angiogenesis effects on the cardiac tissue through different pathways.  The aim of present study was to investigate the effects of 4 weeks aerobic training on levels of ROS and NO and gene expression of HIF-1α and VEGF of cardiac tissue in type 2 diabetic male wistar rats. Materials and Methods: In an experimental study, 30 male wist...

Journal: :Molecular medicine reports 2015
Sheng-Li Yang Chao Wu Zhi-Fan Xiong Xiefan Fang

Hypoxia inducible factors (HIFs) are transcription factors, which are commonly expressed in mammals, including humans. The HIFs consist of hypoxia-regulated α and oxygen-insensitive β subunits, and are key regulators of gene expression during hypoxia in normal and solid tumor tissues. Three members of the HIF family, HIF-1α, HIF-2α, and HIF-3α, are currently known. HIF-3α differs from HIF-1α an...

Journal: :Journal of the American Society of Nephrology : JASN 2003
Paul B Freeburg Barry Robert Patricia L St John Dale R Abrahamson

The heterodimeric transcription factors, hypoxia-inducible factor (HIF)-1 and HIF-2, are essential for the maintenance of cellular oxygen homeostasis. In response to hypoxia, stabilized HIF-1alpha and HIF-2alpha proteins bind HIF-1beta and initiate expression of genes that alleviate hypoxic stress, including those promoting neovascularization. Both HIF-1 and HIF-2 stimulate transcription of vas...

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