OBJECTIVE To investigate the relation between measures of pain threshold and symptoms of distress to determine if fibromyalgia is a discrete construct/ disorder in the clinic. METHODS 627 patients seen at an outpatient rheumatology centre from 1993 to 1996 underwent tender point and dolorimetry examinations. All completed the assessment scales for fatigue, sleep disturbance, anxiety, depressi...

STUDY OBJECTIVES To assess the accuracy of a wrist-worn device (Watch_PAT 100) to diagnose obstructive sleep apnea in the home. DESIGN Participants completed 2 overnight diagnostic studies with the test device: 1 night in the laboratory with concurrent polysomnography and 1 night in the home with only the Watch_PAT. The order of the laboratory and home study nights was random. The frequency o...

The primary objective of a prospective study conducted over the July 1976-August 1977 period, as part of the joint project of the University of North Sumatra, Medan and the University of Amsterdam, was to determine the duration of prevention against hypovitaminosis A by 1 oral dose of 300,000 IU vitamin A. At 3-month intervals children were examined critically, fresh stool specimens were analy...

Climate change is one of the main challenges facing agricultural sector as it strives to meet global food needs. In arid and semiarid areas, scarcity water imposes use alternative sources - such reclaimed (RW) or desalinated (DW) deficit irrigation strategies, regulated (RDI), in order maintain productivity. The impact both RDI strategies on soil microbial communities conjunction with crop resp...

Recently, it has been reported that the relative dose intensity (RDI) of adjuvant chemotherapy (AC) influences survival in various cancers, but there are very few reports about RDI in pancreatic ductal adenocarcinoma (PDAC). The optimal timing for initiation of AC for PDAC also remains unknown. The aim of this study was to identify the significance of RDI and the time interval between surgery a...