We describe a gamma-ray imaging camera (GIC) for active interrogation of explosives being developed by NASAIGSFC and NSWCICarderock. The GIC is based on the Three-dimensional Track Imager (3-DTI) technology developed at GSFC for gamma-ray astrophysics. The 3-DTI, a large volume time-projection chamber, provides accurate, -0.4 mm resolution, 3-D tracking of charged particles. The incident direct...

Diffusion tensor imaging (DTI) is a magnetic resonance technique capable of measuring the magnitude and direction of water molecule diffusion in various tissues. The use of DTI is being expanded to evaluate a variety of spinal cord disorders both for prognostication and to guide therapy. The purpose of this article is to review the literature on spinal cord DTI in both animal models and humans ...

Abstract Studying the interaction between drugs and targets is key step of drug repositioning. Through machine learning methods, we can provide reliable drug-target pairs for (DTI) identification wet-lab experiments improve its efficiency. Previous methods did not combine node attributes relationships target, which limited performance those methods. To this end, propose a prediction method that...

System-generated alerts are ubiquitous in personal computing and, with the proliferation of mobile devices, daily activity. While these interruptions provide timely information, research shows they come at a high cost in terms of increased stress and decreased productivity. This is due to dual-task interference (DTI), a cognitive limitation in which even simple tasks cannot be simultaneously pe...

Background and Aim: Diffusion Tensor Imaging (DTI)-based tractography can help us visualize the spatial relation of fiber tracts to brain lesions. Several factors may interfere with procedure diffusion-based tractography, especially in tumors. The current study aims discuss several solutions improve reconstruction adjacent or inside Illustrative cases are also presented. Methods Materials/Patie...

BACKGROUND AND PURPOSE DTI is a promising technique for imaging of the spinal cord, but the technique has susceptibility-induced artifacts. We evaluated a pulse-triggered DTI sequence with an rFOV technique and coronal acquisition for the assessment of the cervical spinal cord in patients with myelitis at 3T. MATERIALS AND METHODS A rFOV acquisition was established by a noncoplanar applicatio...

Objective: The potential of magnetic resonance imaging (MRI) as a technical biomarker for cerebral microstructural alterations in neurodegenerative diseases is under investigation. In this study, a framework for the longitudinal analysis of diffusion tensor imaging (DTI)-based mapping was applied to the assessment of predefined white matter tracts in amyotrophic lateral sclerosis (ALS), as an e...

BACKGROUND Glioma surgery in eloquent areas remains a challenge because of the risk of postoperative motor deficits. OBJECTIVE To prospectively evaluate the efficiency of using a combination of diffusion tensor imaging (DTI) tractography functional neuronavigation and direct subcortical stimulation (DsCS) to yield a maximally safe resection of cerebral glioma in eloquent areas. METHODS A pr...

Tractography is typically performed for each subject using the diffusion tensor imaging (DTI) data in its native subject space rather than in some space common to the entire study cohort. Despite performing tractography on a population average in a normalized space, the latter is considered less favorably at the individual subject level because it requires spatial transformations of DTI data th...

BACKGROUND Evidence suggests that white matter integrity may play an underlying pathophysiological role in schizophrenia. N-acetylaspartate (NAA), as measured by Magnetic Resonance Spectroscopy (MRS), is a neuronal marker and is decreased in white matter lesions and regions of axonal loss. It has also been found to be reduced in the prefrontal and temporal regions in patients with schizophrenia...