Background: The achievement of an effective compound for prevention/treatment of hypertension with fewer complications has been of interest in recent years. OBJECTIVES: This study aimed to examine the effects of L-citrulline pretreatment on the tension of isolated rat aortic tissues precontracted by different vasoconstrictors. METHODS: Sixteen male Wistar rats (300-350g) were randomly divided i...

9These PROCUODINGS, 4, 1918 (364-370). 10 Compare the argument from here on with that on pages 337-339 of my paper, "Concerning simple continuous curves," loc. cit. 1 Mazurkiewicz, S., loc. cit., p. 123. 12 Cf. Hahn, H., Wien. Ber., 123, 1914 (2433). 13 Janiszewski, S., "Sur les continius irreductibles entre deux points," J. I'Ecole Polytech. 16, 1911-1912 (79-170). 14 Mazurkiewicz, S., loc. ci...

Combinatorial Interaction Testing (CIT) is important because it tests the interactions between the many parameters that make up the configuration space of software systems. We apply this testing paradigm to a Python-based framework for rapid development of webbased applications called Django. In particular, we automatically create a CIT model for Django website configurations and run a state-of...

BACKGROUND The aim of the present study was to determine the effects of cold ischaemia time (CIT) on living donor kidney transplant recipients in a large national data set. METHODS Data from the National Health Service Blood and Transplant and UK Renal Registry databases for all patients receiving a living donor kidney transplant in the UK between January 2001 and December 2014 were analysed....

Vascular endothelial dysfunction and inflammatory response are early events during initiation and progression of atherosclerosis. In vitro studies have described that CIT markedly upregulates expressions of ICAM-1 and VCAM-1 of endothelial cells, which result from NF-κB activation induced by CIT. In order to determine whether it plays a role in atherogenesis in vivo, we conducted the study to i...

OBJECTIVE It is aimed to characterize the true relationship of the cold ischemia time (CIT) with graft survival and with the principal post-transplantation events. MATERIAL AND METHODS We analyzed 378 kidney transplants, studying the relationship of the CIT with graft survival using a univariate analysis according to the COX model and seeking the optimum cutoff according to the Kaplan-Meier m...

UNLABELLED BACKGROUND Iodine-123-β-CIT, a single-photon emission computed tomography (SPECT) ligand for dopamine transporters (DATs), has been used for in vivo studies in humans, monkeys, and rats but has not yet been used extensively in mice. To validate the imaging and analysis methods for preclinical DAT imaging, wild-type healthy mice were scanned using 123I-β-CIT. METHODS The pharmaco...

Cluster Identification Tool (CIT) is a microarray analysis program that identifies differentially expressed genes. Following division of experimental samples based on a parameter of interest, CIT uses a statistical discrimination metric and permutation analysis to identify clusters of genes or individual genes that best differentiate between the experimental groups. CIT integrates with the free...

[Purpose] Although cardiac rehabilitation (CR) is recommended for patients with chronic heart failure (CHF), adequate exercise effect cannot be obtained in elderly patients. Administration of amino acids (AA) to CHF patients has been reported to improve exercise capacity, but the changes in AA composition in plasma before and after CR had not been reported. This study aimed to measure plasma le...

INTRODUCTION The ability to preserve organs prior to transplant is essential to the organ allocation process. OBJECTIVE The purpose of this study is to describe the functional relationship between cold-ischemia time (CIT) and primary nonfunction (PNF), patient and graft survival in liver transplant. METHODS To identify relevant articles Medline, EMBASE and the Cochrane database, including t...