Developing a mathematical model for the artificial generation of electrocardiogram (ECG) signals is a subject that has been widely investigated. One of its uses is for the assessment of diagnostic ECG signal processing devices. So the model should have the capability of producing a wide range of ECG signals, with all the nuances that reflect the sickness to which humans are prone, and this ...

HRV (heart rate variability) analysis is a widely employed method to assess cardiac autonomic nervous system activity. Accurate HRV measurement is critical to its value as a diagnostic and prognostic tool. Different breathing patterns may affect HRV, but results obtained under static conditions are conflicting. HRV indices decrease considerably during systemic inflammation evoked by experimenta...

BACKGROUND Human rhinoviruses (HRV) cause a wide spectrum of disease, ranging from a mild influenza-like illness (ILI) to severe respiratory infection. Molecular epidemiological data are limited for HRV circulating in the Southern Hemisphere. OBJECTIVES To identify the species and genotypes of HRV from clinical samples collected in Sydney, Australia, from 2006 to 2009. METHODS Combined nose...

Background The newly identified HRV-C has been linked to more severe symptoms of asthma and an increased risk of prior and subsequent hospital admission. Our research team has recently reported that despite their sequence dissimilarity, the HRV-A and HRV-C species have a high degree of antibody cross-reactivity and the HRV-C specific antibody response is low (Iwasaki et al., 2013). This study a...

Human rhinoviruses (HRV) usually cause upper airway infections. However, viral replication in the tracheobronchial tree has been disclosed, although its clinical role is poorly known. We evaluated the prevalence of HRV in 159 bronchoalveolar lavages from 88 patients and describe a lung transplant recipient with a high HRV load in association with acute rejection. HRV was detected in 22/88 patie...

Human rhinovirus (HRV) infections are common but poorly characterized in university students. Thus, we characterized asymptomatic and symptomatic HRV infections by incidence, species diversity, and viral load of 502 university students during September and October of 2010 and 2011 from nasal swabs and electronically submitted symptom questionnaires. We tested all symptomatic students and random...

Heart rate variability (HRV) is generated by the interaction of multiple regulatory mechanisms that operate on different time scales. This article examines the regulation of the heart, the meaning of HRV, Thayer and Lane’s neurovisceral integration model, the sources of HRV, HRV frequency and time domain measurements, Porges’s polyvagal theory, and resonance frequency breathing. The medical imp...

We read with interest the recent paper by Xiang and colleagues describing the molecular epidemiology of human rhinovirus in China. Human rhinoviruses (HRVs) were first discovered more than 50 years ago. HRVs are a common cause of upper respiratory tract infections, but are also associated with asthma exacerbations and more severe respiratory infections. HRVs can be divided into three groups, A,...

OBJECTIVE Decreased cardiac vagal control (CVC) has been proposed in posttraumatic stress disorder (PTSD), but the results are mixed. Analyses with larger sample sizes and better methodology are needed. METHODS Thirty-two drug-naïve survivors with current PTSD, 32 survivors without PTSD and 192 matched controls were recruited for a case-control analysis. We used the PTSD checklist-civilian ve...