نتایج جستجو برای: سیتوکراتین 18 ck

تعداد نتایج: 358984  

Journal: :Cancer research 1991
R B Lichtner J A Julian S M North S R Glasser G L Nicolson

We used immunohistochemical procedures to study the cellular expression and distribution of cytokeratins (CKs) in rat 13762NF mammary adenocarcinoma cells growing at mammary fat pad sites and at spontaneous lymph node and lung sites. In order to establish CK distribution in normal rat mammary epithelia, immature, resting, and lactating rat mammary glands were probed with a panel of monospecific...

2014
Hayam A Aiad Rehab M Samaka Nancy Y Asaad Mona A Kandil Mohamed A Shehata Islam M Miligy

The immunohistochemical (IHC) subtyping of breast cancer can be a useful substitute for gene expression analysis. The aim of this study was to investigate the relationship of CK8/18 to the biology of breast carcinoma (BC) represented by its IHC subtypes. The IHC expression of CK8/18 was correlated with IHC subtypes of BC using ER, PR, HER2/neu, and Ki67 LI (with cutoff 14%). All cases showed CK...

Journal: :Journal of the American College of Cardiology 2002
Neal S Kleiman Nasser Lakkis Christopher P Cannon Sabina A Murphy Peter M DiBattiste Laura A Demopoulos William S Weintraub Eugene Braunwald

OBJECTIVE We sought to determine whether elevation of plasma creatine kinase muscle-brain fraction (CK-MB) would be useful to triage patients with acute coronary syndromes (ACS) to early angiography/revascularization. BACKGROUND It is unknown whether the measurement of CK-MB is effective for triage to an aggressive management strategy. METHOD Patients in the Treat Angina With Aggrastat and ...

Journal: :Fukushima journal of medical science 2015
Hidetoshi Kinoshita Takashi Imamura Hajime Maeda Yasuko Shibukawa Yutaka Fukuda Shogo Kin Hiromichi Ariga Katsutoshi Nagasawa

Several studies have shown that brain hypothermia therapy (BHT) after neonatal hypoxic-ischemic encephalopathy (HIE) can improve neurodevelopmental outcomes. However, there have been no reports of the neurodevelopmental outcomes for the infant with a serum creatine kinase (CK) level above 20,000 IU/L in association with neonatal HIE. We report a female infant with a very high serum CK level (26...

2016
Nathalia Carolina Fernandes Fagundes Luanna Melo Pereira Fernandes Ricardo Sousa de Oliveira Paraense Paulo Mecenas Alves de Farias-Junior Francisco Bruno Teixeira Sergio Melo Alves-Junior João de Jesus Viana Pinheiro Maria Elena Crespo-López Cristiane Socorro Ferraz Maia Rafael Rodrigues Lima

This study investigates morphological and biochemistry effects of binge ethanol consumption in parotid (PG) and submandibular (SG) salivary glands of rats from adolescence to adulthood. Female Wistar rats (n = 26) received ethanol at 3 g/kg/day (20% w/v) for 3 consecutive days/week from the 35th until the 62nd day of life. Animals were treated in two periods: 1 week (G1) and 4 weeks (G2), with ...

2014
T. Mpakama A. Y. Chulayo V. Muchenje

The objective of the study was to determine the effects of animal related factors on bruising in slaughter cattle, creatine kinase (CK) and beef quality. Three hundred and twenty one cattle from three breeds (108 Bonsmara, 130 Beefmaster and 83 Brahman) were used in this study. The animals were grouped as follows: Group 1 (16 months old), Group 2 (18 months old) and Group 3 (24 months old). At ...

Journal: :Blood 2012
Frank G Rücker Richard F Schlenk Lars Bullinger Sabine Kayser Veronica Teleanu Helena Kett Marianne Habdank Carla-Maria Kugler Karlheinz Holzmann Verena I Gaidzik Peter Paschka Gerhard Held Marie von Lilienfeld-Toal Michael Lübbert Stefan Fröhling Thorsten Zenz Jürgen Krauter Brigitte Schlegelberger Arnold Ganser Peter Lichter Konstanze Döhner Hartmut Döhner

To assess the frequency of TP53 alterations and their correlation with other genetic changes and outcome in acute myeloid leukemia with complex karyotype (CK-AML), we performed integrative analysis using TP53 mutational screening and array-based genomic profiling in 234 CK-AMLs. TP53 mutations were found in 141 of 234 (60%) and TP53 losses were identified in 94 of 234 (40%) CK-AMLs; in total, 1...

Journal: :American journal of physiology. Renal physiology 2011
Minolfa C Prieto Romer A González-Villalobos Fady T Botros Victoria L Martin Javier Pagán Ryousuke Satou Lucienne S Lara Yumei Feng Fernanda B Fernandes Hiroyuki Kobori Dulce E Casarini L Gabriel Navar

Alterations in the balance between ANG II/ACE and ANG 1-7/ACE2 in ANG II-dependent hypertension could reduce the generation of ANG 1-7 and contribute further to increased intrarenal ANG II. Upregulation of collecting duct (CD) renin may lead to increased ANG II formation during ANG II-dependent hypertension, thus contributing to this imbalance. We measured ANG I, ANG II, and ANG 1-7 contents, a...

Journal: :European heart journal 2005
Claudio Cavallini Stefano Savonitto Roberto Violini Gustavo Arraiz Mario Plebani Zoran Olivari Paolo Rubartelli Salvatore Battaglia Luigi Niccoli Giuseppe Steffenino Diego Ardissino

AIMS Retrospective studies and post hoc analyses have suggested that mild elevations in the creatine kinase-MB (CK-MB) isoenzyme following percutaneous coronary intervention (PCI) may be associated with an increased risk of death in the long term. However, this finding is still controversial, and the prognostic significance of elevations of more sensitive markers of myocardial damage, such as t...

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