نتایج جستجو برای: سوییچ ovs
تعداد نتایج: 482 فیلتر نتایج به سال:
در این مقاله یک مبدل دو طرفه جدید ایزوله ارائه شده است. این مبدل از دو ترانسفورمر فوروارد و فلای بک تشکیل گردیده و تنها یک سوییچ در طرف اولیه و یک سوییچ در طرف ثانویه ترانسفورمر دارد. این مبدل به صورت pwm کنترل می گردد و از آنجایی که در هر دو حالت خاموش و روشن بودن سوییچها توان به خروجی منتقل می گردد، چگالی توان آن نسبت به مبدلهای قبلی بالاتر است. از طرفی مبدل مذکور قادر است که از هر دو طرف به ...
Intratumoral innate immunity can play a significant role in blocking the effective therapeutic spread of a number of oncolytic viruses (OVs). Histone deacetylase inhibitors (HDIs) are known to influence epigenetic modifications of chromatin and can blunt the cellular antiviral response. We reasoned that pretreatment of tumors with HDIs could enhance the replication and spread of OVs within mali...
Oncolytic viruses (OVs) are being extensively studied for their potential roles in the development of cancer therapy regimens. In addition to their direct lytic effects, OVs can initiate and drive systemic antitumor immunity indirectly via release of tumor antigen, as well as by encoding and delivering immunostimulatory molecules. This combination makes them an effective platform for the develo...
In what proved to be probably the most influential Principles-andParameters manuscript of the last year, Kayne (1993) has proposed 1) a Linear Correspondence Axiom which together with a particular definition of (asymmetric) c-command is supposed to allow only SVO and OVS as underlying word orders and 2) an abstract beginning node asymmetrically ccommanding all other nodes which is supposed to f...
Two visual world eye-tracking studies investigated the effect of emotions and actions on sentence processing. Positively emotionally valenced German non-canonical object-verb-subject (OVS) sentences were paired with a scene depicting three characters (agent-patient-distractor) as either performing the action described by the sentence, or not performing any actions. These scene-sentence pairs we...
The oviductal epithelial membrane releases into the luminal environment extracellular vesicles (EVs) which are pleomorphic in nature and fall into two categories: exosomes and microvesicles. Both of these membrane vesicles are referred to as Oviductosomes (OVS), and to date have been identified in the murine and bovine species. Bovine EVs derived in vivo and from in vitro culture show differenc...
Although counteracting innate defenses allows oncolytic viruses (OVs) to better replicate and spread within tumors, CD8(+) T-cells restrict their capacity to trigger systemic anti-tumor immune responses. Herpes simplex virus-1 (HSV-1) evades CD8(+) T-cells by producing ICP47, which limits immune recognition of infected cells by inhibiting the transporter associated with antigen processing (TAP)...
Oncolytic viruses (OVs) are unique anticancer agents based on their pleotropic modes of action, which include, besides viral tumor cell lysis, activation of antitumor immunity. A panel of diverse viruses, often genetically engineered, has advanced to clinical investigation, including phase 3 studies. This diversity of virotherapeutics not only offers interesting opportunities for the implementa...
Despite the importance of the adjuvant in the immunization process, very few adjuvants merge with the antigens in vaccines. A synthetic self-adjuvant oleic-vinyl sulfone (OVS) linked to the catalytic region of recombinant serine/threonine phosphatase 2A from the nematode Angiostrongylus costaricensis (rPP2A) was used for intranasal immunization in mice previously infected with Trichuris muris T...
This study examines agrammatic comprehension of object-subject-verb (OSV) and object-verb-subject (OVS) structures in Hebrew. These structures are syntactically identical to the basic order subject-verb-object (SVO) sentence except for the movement of the object to the beginning of the sentence, and thus enable empirical examination of syntactic movement in agrammatic comprehension. Seven indiv...
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