Although considerable research has been conducted in recent years on the mechanisms of fatty acid synthesis and oxidation in animal tissues (1) and in microorganisms (2), no similar studies of higher plants have yet been reported, despite the great importance of fat-storing seeds and fruits in the economy of nature and the value to comparative biochemistry of an understanding of fatty acid biog...

The microstructures of two metal hydride (MH) alloys, a Zr7Ni10 based Ti15Zr26Ni59 and a C14 Laves phase based Ti12Zr21.5V10Ni36.2Cr4.5Mn13.6Sn0.3Co2.0Al0.4, were studied using the electron backscatter diffraction (EBSD) technique. The first alloy was found to be composed of completely aligned Zr7Ni10 grains with a ZrO2 secondary phase randomly scattered throughout and a C15 secondary phase pre...

AIM Cationic ethylphosphatidylcholines (ePCs) were evaluated for the delivery of siRNA in modified breast cancer cells. MATERIALS AND METHODS Dimyristoleoyl-ePC (C14), dioleoyl-ePC (C18), and dilauroyl-ePC (C12) nanoparticles were complexed with siRNA for green fluorescent protein (GFP) suppression in modified MCF-7 breast cancer cells. The kinetics of GFP suppression were followed over the c...

Weinhouse and co-workers (39-43) have estab lished that the Krebs tricarboxylic acid cycle operates in a variety of experimental tumors and that fatty acid oxidation, believed to be non existent in tumors (9), provides 2-carbon frag ments for continuous operation of this cycle in neoplastic tissues. Our studies with the mouse hepatoma C954, carried by mice of the C57-Leaden strain, also led us ...

In experiments preliminary to the possible use of carbon-14-labeled Stilbamidine in the treatment of humans with multiple myeloma (2, 9, 26) it was found in normal mice that no abnormal concentra tion of Stilbamidine persisted in any tissue and that over 90 per cent of the injected radioactivity was excreted within a month (20). A tracer dose of C14-labeled Stilbamidine was then given to a hu m...