This article investigates boosting naive Bayesian classification. It first shows that boosting does not improve the accuracy of the naive Bayesian classifier as much as we expected in a set of natural domains. By analyzing the reason for boosting’s weakness, we propose to introduce tree structures into naive Bayesian classification to improve the performance of boosting when working with naive ...

We augment the naive Bayes model with an n-gram language model to address two shortcomings of naive Bayes text classifiers. The chain augmented naive Bayes classifiers we propose have two advantages over standard naive Bayes classifiers. First, a chain augmented naive Bayes model relaxes some of the independence assumptions of naive Bayes—allowing a local Markov chain dependence in the observed...

Naive Credal Classifier, which is an imprecise-probability counterpart of Naive Bayes, is rigorously extended to a very general and flexible treatment of incomplete data, yielding a new classifier called Naive Credal Classifier 2 (NCC2). The new classifier delivers classifications that are robust to the presence of small sample sizes and missing values. In particular, some empirical evaluations...

To examine directly whether a limited number of naive T cells transferred to lymphopenic hosts can truly fill the peripheral naive T cell pool, we compared the expansion and phenotype of naive T cells transferred to three different hosts, namely recombination-activating gene-deficient mice, CD3epsilon-deficient mice, and irradiated normal mice. In all three recipients, the absolute number of re...

Human pluripotent stem cells (PSCs) exist in naive and primed states and provide important models to investigate the earliest stages of human development. Naive cells can be obtained through primed-to-naive resetting, but there are no reliable methods to prospectively isolate unmodified naive cells during this process. Here we report comprehensive profiling of cell surface proteins by flow cyto...

Children with Down syndrome (DS) have low numbers of naive T cells and abnormal thymus development and function. Because next to thymic production, peripheral proliferation greatly contributes to naive T cell generation in healthy children, we examined the cause of reduced naive T cell numbers in children with DS. Compared with aged matched controls, the total number of signal joint TCR excisio...