نتایج جستجو برای: سرخدار اروپایی taxus bacata l

تعداد نتایج: 622567  

Journal: :European heart journal 2008
Lisette Okkels Jensen Michael Maeng Per Thayssen Evald Hoej Christiansen Knud Noerregaard Hansen Anders Galloe Henning Kelbaek Jens Flensted Lassen Leif Thuesen

AIMS Patients with diabetes have increased risk of in-stent restenosis after coronary stent implantation owing to neointimal hyperplasia (NIH). The aim of the study was to evaluate the extent and distribution of NIH with intravascular ultrasound (IVUS) after coronary artery stenting with sirolimus-eluting (Cypher) or paclitaxel-eluting (Taxus) stents in diabetic patients. METHODS AND RESULTS ...

2010
Juan F Granada Barbara A Huibregtse Keith D Dawkins

Patients with diabetes mellitus, of female gender, increased age, and/or with peripheral vascular disease often develop coronary stenoses in small caliber vessels. This review describes treatment of these lesions with the paclitaxel-eluting 2.25 mm TAXUS(®) Liberté(®) Atom™ stent. Given the same stent composition, polymer, antirestenotic drug (paclitaxel), and release kinetics as the first-gene...

Journal: :European heart journal 2007
Eberhard Grube Keith D Dawkins Giulio Guagliumi Adrian P Banning Krzysztof Zmudka Antonio Colombo Leif Thuesen Karl Hauptman Jean Marco William Wijns Jeffrey J Popma Lutz Buellesfeld Joerg Koglin Mary E Russell

AIMS Drug-eluting stents (DESs) have shown to be effective in reducing in-stent restenosis, although data relating to long-term experience in treating more complex lesion subsets are limited. In order to assess the long-term safety and clinical efficacy of the polymer-based moderate release (MR) paclitaxel-eluting TAXUS MR stent in treatment of complex lesion subsets, we evaluated the 2-year fo...

Journal: :Circulation 2003
Eberhard Grube Sigmund Silber Karl Eugen Hauptmann Ralf Mueller Lutz Buellesfeld Ulrich Gerckens Mary E Russell

BACKGROUND The TAXUS NIRx stent (Boston Scientific Corp) provides local delivery of paclitaxel via a slow-release polymer coating. The TAXUS I trial was the first in-human experience evaluating safety and feasibility of the TAXUS NIRx stent system compared with bare NIR stents (control) (Boston Scientific Corp) for treatment of coronary lesions. METHODS AND RESULTS METHODS AND RESULTS The ...

Journal: :Horticulturae 2022

Paclitaxel (Taxol®) is a potent anticancer agent, but the widespread pharmaceutical use of paclitaxel hampered by its limited availability due to low accumulation levels in native yew (Taxus spp.) plants. Currently, hairy root culture an emerging biotechnological tool that presents several advantages such as reduced costs and higher specialized metabolite production, therefore, application prod...

Journal: :BioImpacts : BI 2011
Ahmad Yari Khosroushahi Hossein Naderi-Manesh Henrik Toft Simonsen

INTRODUCTION To control the tissue browning phenomenon, callus growth, total phenolics and paclitaxel production, in the current investigation, we evaluated the effects of citric acid and ascorbic acid (as antioxidants) and glucose, fructose and sucrose in callus cultures of Taxus brevifolia. METHODS To obtain healthy callus/cell lines of Taxus brevifolia, the effects of two antioxidants asco...

Journal: :Trials 2009
Jae-Bin Seo Hui-Kyung Jeon Kyung-Woo Park Jong-Seon Park Jang-Ho Bae Sang-Wook Kim Keon-Woong Moon Jae-Woong Choi Sang-Gon Lee Woo-Young Chung Tae-Jin Youn Soo-Joong Kim Doo-Il Kim Byung-Ok Kim Min-Su Hyon Keum-Soo Park Tae-Joon Cha Hweung-Kon Hwang Seung-Ho Hur Hyo-Soo Kim

BACKGROUND Previous randomized trials have showed the superiority of Paclitaxel-eluting stent over bare metal stent in angiographic and clinical outcomes. Coroflex Please stent is a newly developed drug eluting stent using the Coroflex stent platform combined with the drug paclitaxel contained in a polymer coating. PECOPS I trial, one-arm observational study, showed that the clinical and angiog...

L. Delshad, M. Ghaedi M. Yousefi Nejad

Plants are rich source of natural products used for centuries to cure various the plant-derived medicines are based upon the premise that they contain natural substances that can promote health and alleviate illness. Silver NPs represent material, which can be used as a potential antibacterial agent in medical applications and different commercial products due to its biological activity. Recent...

2015
Meiya Li Fusheng Jiang Xiangli Yu Zhiqi Miao

Taxadiene is the first committed precursor to paclitaxel, marketed as Taxol, arguably the most important anticancer agent against ovarian and breast cancer. In Taxus, taxadiene is directly synthesized from geranylgeranyl diphosphate (GGPP) that is the common precursor for diterpenoids and is found in most plants and microbes. In this study, Artemisia annua L., a Chinese medicinal herb that grow...

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