BACKGROUND There is a paucity of data about the best lipid ratio predicting the severity of coronary artery disease (CAD) in patients with diabetes mellitus. We determined the relationship between five conventional lipid ratios and the extent of coronary artery lesions in Chinese Type 2 diabetics with stable angina pectoris (SAP). METHODS A prospective cohort study within 373 type 2 diabetic ...

BACKGROUND/AIMS Human paraoxonase-1 (PON1) is responsible for the antioxidant effect of high-density lipoprotein (HDL) by inhibiting low-density lipoprotein oxidation. Previous studies discovered dyslipidemia (DL) and decreased PON1 activity in chronic renal failure (CRF). We aimed to determine PON and arylesterase activity, phenotypic distribution of the PON1 enzyme, and lipid profile in low a...

BACKGROUND We examined the predictive value of various clinical and biochemical markers for angiographically defined coronary artery disease (aCAD). Specifically, we assessed the value of the ratio of plasma triglyceride (TGs) to HDL-cholesterol (HDL-C) and the fractional esterification rate of cholesterol in plasma depleted of apolipoprotein B (apoB)-containing lipoproteins (FER(HDL)), a funct...

BACKGROUND AND AIMS High-density lipoproteins (HDLs) may directly stimulate β-cell function and glucose metabolism. We determined the relationships of fasting high-density lipoprotein cholesterol (HDL-C), plasma apolipoprotein (apo) A-I and apoA-II, and HDL-C-to-apoA-I and HDL-C-to-apoA-II ratios, as estimates of HDL particle composition, with incident type 2 diabetes mellitus. METHODS A pros...

Aims: Tobacco smoking is a major health issue in Saudi Arabia, particularly among the student population. Smoking one of risk factors genesis coronary atherosclerosis and development heart disease. This study aimed to evaluate effect cigarette shisha on atherogenic indexes, lipid profile hematological parameters undergraduate smokers at Majmaah University.
 Methodology: cross-sectional was...

BACKGROUND High-density lipoproteins (HDL) are structurally and metabolically heterogeneous and subclasses with differential effects on coronary heart disease (CHD) might exist. Apolipoprotein (apo) C-III, a small proinflammatory protein that resides on the surface of lipoproteins, enhances the atherogenicity of VLDL and LDL particles, but little is known about the role apoC-III on HDL. We inve...

Regular physical activity with adequate intensity, according to WHO recommendations, can prevent various chronic diseases, such as heart disease, diabetes mellitus, cancer, and bone disease. Physical improve lipid profil: triglycerides, total cholesterol, HDL cholesterol (HDL-C), LDL (LDL-C). The aim of this study was compare profiles, which include levels (LDL-C) at different activity: low, me...