The retinoblastoma (Rb) tumor suppressor controls cellular proliferation, survival, and differentiation and is functionally inactivated by mutations or hyperphosphorylation in most human cancers. Although activation of endogenous Rb is thought to provide an effective approach to suppress cell proliferation, long-term inhibition of apoptosis by active Rb may have detrimental consequences in vivo...

In a bus-based mult iprocessor system, a bus arb i t ra t ion c i r c u i t i s necessary to assign the bus(es) to the requesting devices. A number of a rb i te r designs for singlebus mult iprocessor systems a re avai lable in the ex is t ing l i terature. There a re two types o f arb i ters : synchronous and asynchronous. In a synchronous a r b i t e r , the a r b i t r a t i o n process repe...

discovery and analysis of microRNAs (miRNAs) has revealed a new mechanism of gene regulation. miRNAs can base-pair with specific mRNA targets and regulate their expression at the post-transcriptional level [1]. Changes in miRNA abundance are implicated in controlling many biological processes including cellular senescence [2], an irreversible form of growth arrest involved in cellular aging. Th...

In this article, a series of highly boron-doped diamond ([B] > 1021 cm−3) electrodes with small gradient variations in boron concentration were prepared by hot filament chemical vapor deposition (HF-CVD). Reactive blue 19 (RB-19) dye solution was used as prototype wastewater. Interestingly, we found that the electrochemical properties (electrochemically active surface area and oxygen evolution ...

Nanostructured hybrid thin films of CuSCN and rhodamine B (RB) are electrochemically self-assembled (ESA) by cathodic electrolysis in an ethanol/water mixture containing Cu2+, SCN-, and RB. By selecting the solvent, Cu2+/SCN- ratio, and the concentration of RB, we demonstrate several control parameters in the film formation. High loading of RB into the film has been achieved to reach a CuSCN:RB...

Elevated cyclic AMP levels induce a rapid block in the mid-G1 phase of the cell cycle in B-lymphoid Reh cells, accompanied by a transient block in G2. The retinoblastoma (Rb) gene product has been implicated as a key regulator of eukaryotic cell growth. The Rb protein enforces its growth-suppressive effect in early G1, where it is underphosphorylated and firmly bound in the nucleus. A possible ...

In the article we propose a new compression method (to 2⌈log2⁡(q)⌉+3 bits) for Fq2-points of an elliptic curve Eb:y2=x3+b (for b∈Fq2⁎) j-invariant 0. It is based on Fq-rationality some generalized Kummer surface GKb. This geometric quotient Weil restriction Rb:=RFq2/Fq(Eb) under order 3 automorphism restricted from Eb. More precisely, apply theory conic bundles (i.e., conics over function field...

for $a,bin m_{nm},$ we say that $a$ is left matrix majorized (resp. left matrix submajorized) by $b$ and write $aprec_{ell}b$ (resp. $aprec_{ell s}b$), if $a=rb$ for some $ntimes n$ row stochastic (resp. row substochastic) matrix $r.$ moreover, we define the relation $sim_{ell s} $ on $m_{nm}$ as follows: $asim_{ell s} b$ if $aprec_{ell s} bprec_{ell s} a.$ this paper characterizes all linear p...

An axis-parallel b-dimensional box is a Cartesian product R1 ×R2 × . . .× Rb where each Ri (for 1 ≤ i ≤ b) is a closed interval of the form [ai, bi] on the real line. The boxicity of any graph G, box(G) is the minimum positive integer b such that G can be represented as the intersection graph of axis parallel b-dimensional boxes. A b-dimensional cube is a Cartesian product R1 × R2 × . . . × Rb,...

A technique has been developed to estimate the internal battery temperature (Tbat) of secondary batteries by measuring the series battery resistance R ) at cold ambient temperatures. Tests were performed on both lead-acid and nickel metal hydride batteries at different cold temperatures to B btain useful plots of RB versus Tbat. RB was measured by using a pulse discharge circuit to apply a shor...