نتایج جستجو برای: رگرسیون cox
تعداد نتایج: 85683 فیلتر نتایج به سال:
Abstract Background: Lung cancer is one of the most common cancers around the world. The aim of this study was to use Extended Cox Model (ECM) with Bayesian approach to survey the behavior of potential time-varying prognostic factors of Non-small cell lung cancer. Materials and Methods: Survival status of all 190 patients diagnosed with Non-Small Cell lung cancer referring to hospitals in ...
A group of 1,3-biarylhydrazide derivatives possessing a COX-2 azido pharmacophore at the Para- position of the C-1 phenyl ring in conjunction with a N-3 phenyl or substituted-phenyl ring (4-F,4-Cl,4-OMe) were designed and synthesized based on nucleophilic substitution reaction. A molecular modelling study of these compounds showed that the designed molecules were well bound with the active site...
سندرم تخمدان پلی کیستیک(pcos) اختلال سیستم تولیدمثلی و نارسایی اندوکرینی است که با رشد سریع اولیه ی فولیکولی و عدم انتخاب یک فولیکول غالب از ذخیره ی افزایش یافته ی فولیکولی، هایپراندروژنیسم، افزایش آنژیوژنز، جریان خون تخمدانی و متعاقبا عدم تخمک گذاری مزمن همراه است. این سندرم همچنین به عنوان یک بیماری التهابی با افزایش سطح سیتوکین ها و نیز افزایش crp سرم معرفی شده است. نظر به اثرات آنژیوژنیک سی...
conclusions the use of smoothing methods helps us to eliminate non-linear effects but it is more appropriate to use cox proportional hazards model in medical data because of its’ ease of interpretation and capability of modeling both continuous and discrete covariates. also, cox proportional hazards model and smoothing methods analysis identified that age at diagnosis and tumor size were indepe...
as a continuous research for discovery of new cox-2 inhibitors, chemical synthesis, in vitro biological activity and molecular docking study of anew group of 1,4-dihydropyridine (dhp) derivatives were presented. novel synthesized compounds possessing a cox-2 so2me pharmacophore at the para position of c-4 phenyl ring, different hydrophobic groups (r1) at c-2 position and alkoxycarbonyl groups (...
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