A number of mathematical models have been tested for their suitability in representing the dose response curve of a specific assay of the hormone human placental lactogen (HPL).(1)A new equation Y = B[0.14 + 1/[1 + C log [1 + exp[X - D]]] where Y is the percentage activity or counts bound to the antibody and X is the HPL concentration is proposed as representing the overall shape of the curve. ...

The High Performance Conjugate Gradient (HPCG) benchmark has been recently proposed as a complement to the High Performance Linpack (HPL) benchmark currently used to rank supercomputers in the Top500 list. This new benchmark solves a large sparse linear system using a multigrid preconditioned conjugate gradient (PCG) algorithm. The PCG algorithm contains the computational and communication patt...

The use of heterogeneous devices is becoming increasingly widespread. Their main drawback is their low programmability due to the large amount of details that must be handled. Another important problem is the reduced code portability, as most of the tools to program them are vendor or device-specific. The exception to this observation is OpenCL, which largely suffers from the reduced programmab...

A fatty acid hydroperoxidelyase (HPL) enzyme from soybean (Glycine max) seeds was purified by ammonium sulphate precipitation followed by ion exchange chromatography on DEAE-Cellulose and DEAE-Sephacel. HPL showed specific activity of 161U/mg with fold purification of 16.4 and enzyme yield was found to be 9.06%. The purified enzyme on SDSPAGE showed a prominent band of ~53KDa. Kinetic studies w...

Abstract Background South Africa was the first sub-Saharan African country to implement a sugar-sweetened beverage (SSB) tax called Health Promotion Levy (HPL) in April 2018. Given news media can increase public awareness and sway opinions, this study analyzed how represented HPL, including expressions of support or challenge, topics associated with levy, stakeholder views HPL. Methods We perfo...

BACKGROUND AIMS The selection of medium and associated reagents for human mesenchymal stromal cell (hMSC) culture forms an integral part of manufacturing process development and must be suitable for multiple process scales and expansion technologies. METHODS In this work, we have expanded BM-hMSCs in fetal bovine serum (FBS)- and human platelet lysate (HPL)-containing media in both a monolaye...

C6 volatiles are synthesized through lipoxygenase-hydroperoxide lyase (LOX-HPL) pathway and these volatiles play important roles in the aromatic quality of grape berries. This study investigated the evolution of both C6 volatiles and the key genes in the LOX-HPL pathway in different table grape cultivars during the berry development period, and further assessed the correlation between the accum...

The highly conserved Hox transcription factors define positional identity along the anterior-posterior body axis during development. Inappropriate expression of Hox genes causes homeotic transformation, which leads to abnormal development of a specific region or segment. C. elegans offers an excellent model for studying factors required for the establishment of the spatially-restricted expressi...

Hydroperoxide lyase (HPL) cleaves lipid hydroperoxides to produce volatile flavor molecules and also potential signal molecules. We have characterized a gene from Arabidopsis that is homologous to a recently cloned HPL from green pepper (Capsicum annuum). The deduced protein sequence indicates that this gene encodes a cytochrome P-450 with a structure similar to that of allene oxide synthase. T...