Background: Heart failure is a leading cause of death in industrialized nations especially in the aging populations. Novel approaches to treat the heart after acute injury and to improve cardiac hypertrophic remodeling and heart failure processes remain unsatisfactory. Activating transcription factor 3 (ATF3) is a member of the ATF/cAMPresponse elementbinding protein family of transcriptional f...

We present two plug-ins for Protégé OWL. The first, Discovery Tab, supports document-based ontology engineering with relevant term extraction, clustering and related functionality. The second, Annotation Tab, provides a facility to annotate documents manually and automatically (based on a training set).

The c-erbB-2 gene encodes a M(r) 185,000 tyrosine kinase receptor (p185) with extensive homology to the epidermal growth factor receptor. We have conducted mechanistic studies with several anti-p185 monoclonal antibodies (TAb 250, -255, -257, -260, and -263) directed against the extracellular domain of p185 utilizing the SKBR-3, BT-474, and SKOV-3 cancer cell lines. Several of these antibodies ...

This tab-separated database is derived from the Carcinogenic Potency Database (CPDB) of Gold et al. that has been published in several earlier papers. This tab-separated database includes the same information as the plot version, and therefore the methods and guide to the plot provide details on what is summarized here. The CPDB is a single standardized resource of the results of 45 years of ch...

OBJECTIVES To evaluate the effect of regular physical activity on metabolic risk factors and blood pressure in Inuit with high BMI consuming a western diet (high amount of saturated fatty acids and carbohydrates with a high glycemic index). STUDY DESIGN Cross sectional study, comparing Inuit eating a western diet with Inuit eating a traditional diet. METHODS Two physically active Greenland ...

BACKGROUND AND MOTIVATION The high-throughput genomics communities have been successfully using standardized spreadsheet-based formats to capture and share data within labs and among public repositories. The nanomedicine community has yet to adopt similar standards to share the diverse and multi-dimensional types of data (including metadata) pertaining to the description and characterization of...

Objective: To evaluate the reliability and accuracy of 4 electronic devices for determining dental shades. Methods: The 4 devices evaluated were the SpectroShade (spectrophotometer), ShadeVision (digital camera with colorimeter), VITA Easyshade (spectrophotometer), and ShadeScan (digital camera with colorimeter). All of the devices were calibrated according to manufacturer instructions. Three t...