BACKGROUND Branchio-oto-renal (BOR) syndrome is an autosomal dominant disorder characterized by branchial, ear, and renal anomalies. The most common gene mutated in BOR patients is EYA1, the human homolog of the Drosophila eyes absent gene, while mutations in SIX1 gene, the human homolog of sine oculis, encoding a DNA binding protein interacting with EYA1, have been reported less frequently. Re...

This paper introduces an automatic tuning method of the tiling parameters required in the implementation of the three-dimensional FDTD method based on time-space tiling. The tuned tiled FDTD kernel was multi-threaded and its performance was evaluated on a multi-core processor. Compared with a naïvely implemented kernel, this tuned FDTD kernel performed better by more than a factor of two.

A hybrid method of subgrid FDTD(2,2) with FDTD(2,4) is presented. Both the standard FDTD(2,2) as well as the hybrid technique are applied to shielding effectiveness analysis of a scaled model of a Boeing 757. Also, analysis of EMI generated by personal electronic devices is performed on the same scaled fuselage model.

We use the eta invariant to compute the equivariant spin bor-dism groups spin 5

The National Institute for Health and Care Excellence (NICE), as part of the institute's single technology appraisal (STA) process, invited the manufacturer of pomalidomide (POM; Imnovid®, Celgene) to submit evidence regarding the clinical and cost effectiveness of the drug in combination with dexamethasone (POM + LoDEX) for the treatment of relapsed and refractory multiple myeloma (RRMM) after...

| Perfectly Matched Layers (PML) are derived for cylindrical and spherical FDTD grids. The formulation relies on the complex coordinate stretching approach. 2D cylindrical and 3D spherical staggered-grid FDTD codes are written based on the time-domain versions of the equations. Numerical simulations validate the formulation by showing very good agreement between the PML-FDTD results and the fre...

in this paper, a new algorithm for studying elastic wave propagation in the phononic crystals is presented. at first, the displacement-based forms of elastic wave equations are derived and then the forms are discretized using finite difference method. so the new algorithm is called the displacement-based finite difference time domain (dbfdtd). three numerical examples are computed with this met...

A new discrete Green’s function formulation of the finite difference time domain (DGF-FDTD) method has been developed which expresses the field response as a convolution of the current sources and the impulse response of the FDTD equation system. DGF-FDTD avoids the need for computation of free space nodes and absorbing boundary conditions. The method has been demonstrated by its application to...

Abstract This is a tutorial paper on the basics and applications of finite-difference time-domain (FDTD) method. Two types discretization linear governing equations, scalar-type FDTD method vector-type one, are first discussed. Then basic concept compact explicit-FDTD (CE-FDTD) described. By considering relationship between cutoff frequency computer resources, it shown that interpolated wide ba...