We tested two hypotheses, first that exercise training reverses age-related decrements in endothelium-dependent dilation in soleus muscle feed arteries and second that this improved endothelium-dependent dilation is the result of increased nitric oxide (NO) bioavailability due to increased content and phosphorylation of endothelial NO synthase (eNOS) and/or increased antioxidant enzyme content....

Jasperse, Jeffrey L., and M. Harold Laughlin. Vasomotor responses of soleus feed arteries from sedentary and exercise-trained rats. J. Appl. Physiol. 86(2): 441–449, 1999.— Our goals were to determine the nature of endotheliumdependent and -independent vascular responses in isolated soleus feed arteries (SFA) and to test the hypothesis that these responses would be altered by exercise training....

Face recognition is a challenging task in computer vision and pattern recognition. It is well-known that obtaining a low-dimensional feature representation with enhanced discriminatory power is of paramount importance to face recognition. Moreover, recent research has shown that the face images reside on a possibly nonlinear manifold. Thus, how to effectively exploit the hidden structure is a k...

We report here on the characterization of the novel immunosuppressant Sanglifehrin A (SFA). SFA is a representative of a class of macrolides produced by actinomycetes that bind to cyclophilin A (CypA), the binding protein of the fungal cyclic peptide cyclosporin A (CsA). SFA interacts with high affinity with the CsA binding side of CypA and inhibits its peptidyl-prolyl isomerase activity. The m...

We tested the hypothesis that age-related endothelial dysfunction in rat soleus muscle feed arteries (SFA) is mediated in part by NAD(P)H oxidase-derived reactive oxygen species (ROS). SFA from young (4 mo) and old (24 mo) Fischer 344 rats were isolated and cannulated for examination of vasodilator responses to flow and acetylcholine (ACh) in the absence or presence of a superoxide anion (O(2)(...

The objective of our study was to resolve two issues pertaining to motoneuron (MN) spike frequency adaptation (SFA): 1) to develop an index of SFA that is sensitive to a wide range of adaptation patterns and would correlate well with MN excitability and 2) to determine whether SFA pattern is stimulus current dependent. Sprague-Dawley rats (250-350 g) were anesthetized (ketamine-xylazine) before...

Dynamic textures exist in various forms, e.g., fire, smoke, and traffic jams, but recognizing dynamic texture is challenging due to the complex temporal variations. In this paper, we present a novel approach stemmed from slow feature analysis (SFA) for dynamic texture recognition. SFA extracts slowly varying features from fast varying signals. Fortunately, SFA is capable to leach invariant repr...

Our goals were to determine the nature of endothelium-dependent and -independent vascular responses in isolated soleus feed arteries (SFA) and to test the hypothesis that these responses would be altered by exercise training. Exercise-trained rats ran 30 m/min, up a 15% grade, 1 h/day, 5 days/wk for 10-12 wk, while sedentary control rats were confined to normal cage activity. SFA were isolated,...

تولید کنندگانی که کارایی پایین تری در تولید گندم دارند می توانند با استفاده از تجربیات سایر تولیدکنندگان، کارایی خود را در طول زمان افزایش دهند. براساس تئوری های موجود، تولید کنندگان با سطوح اولیه پایین کارایی، احتمالا رشد سریع تری نسبت به تولید کنندگان با سطوح بالای کارایی خواهند داشت و یک همگرایی در طول زمان، بین آنها به وجود خواهد آمد. به منظور بررسی همگرایی کارایی هزینه تولید، اطلاعات مربوط...