OBJECTIVE Radiation is an integral part of the treatment of many pelvic tumors. The cellular death induced by radiotherapy (RT) benefits cancer control but can also result in adverse effects (AEs) on the organ being treated or those adjacent to it. RT for cancers of the pelvis (bladder, prostate, rectum, uterus or cervix) can result in AEs in the urinary tract. While the acute urinary AEs of pe...

In recent years, the problem of interpersonal relationships has been reported to be associated with various adolescent psychiatric problems. Egocentrism is one factor related to the problem of interpersonal relationships. The Adolescent Egocentrism-Sociocentrism (AES) scale is used to assess egocentrism in Western countries, but no such scale has been developed in Japan. The purpose of our curr...

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PURPOSE Despite the widespread use of antiepileptic drugs (AEDs) across different neurologic and psychiatric disorders, no study has systematically reviewed all available randomized controlled trials (RCTs) of a given AED to fully uncover its tolerability profile. We aimed at identifying treatment emergent adverse events (AEs) associated with pregabalin through a systematic review and meta-anal...

Objective To assess the safety of azathioprine (AZA) in Japanese patients with antineutrophil cytoplasmic antibody-associated vasculitis (AAV). Methods We retrospectively enrolled 67 consecutive AAV patients who had initiated AZA treatment from January 2006 to August 2014 at Okayama University Hospital. We evaluated the development of severe adverse events (AEs), AZA discontinuation due to tota...

Differential Power Analysis (DPA) is a powerful and practical technique used to attack a cryptographic implementation in a resourcelimited application environment. Despite the extensive research on DPA of AES, it seems none has explicitly addressed the fundamental issue: How far should we protect the first and last parts of AES in order to resist practical DPA attacks, namely first and second-o...

AIMS To identify substantive findings of potential clinical and managerial significance from a regional feasibility study of adverse events (AEs). METHODS A standardised protocol using structured implicit review was applied to 142 AEs generated in an audit study of three public hospitals in the Auckland region for admissions in 1995. Areas of potential significance addressed were: timing, loc...

Rationale Theta oscillations (4-8 Hz) in the hippocampus and the neocortex have been suggested to play a role in the encoding of new memories and long-term plasticity. Intracranial electrode field potential recordings provide high temporal and spatial resolution for studying these oscillations in humans during cognitive tasks. In humans, theta oscillations have been observed in many structures,...

In order to evaluate the effect of pre-heating on biosolubility and water-resistance of alkaline earth silicate (AES) fibers in MgO-SrO-SiO2 and MgO-CaO-SrO-SiO2 compositions, dissolution experiments of the heat-treated (from 110 degrees C to 1,260 degrees C) AES fibers have been carried out in a glycine solution and in distilled water at 40 degrees C for 50 h. The dissolution experiments show ...