In this article, a novel Q-learning scheduling method for the current controller of switched reluctance motor (SRM) drive is investigated. The algorithm class reinforcement learning approaches that can find best forward-in-time solution linear control problem. An augmented system constructed based on reference signal and SRM model to allow solving algebraic Riccati equation current-tracking Thi...

Understanding the basis for differential responses to drug therapies remains a challenge despite advances in genetics and genomics. Induced pluripotent stem cells (iPSCs) offer an unprecedented opportunity to investigate the pharmacology of disease processes in therapeutically and genetically relevant primary cell types in vitro and to interweave clinical and basic molecular data. We report her...

Patients with the long QT syndrome (LQTS) suffer from cardiac arrhythmias that can lead to abrupt loss of consciousness and sudden death, already in young individuals. Thus, an early diagnosis of LQTS is essential for patients and their family members. So far, six genes (KCNQ1, HERG, SCN5A, ANK2, KCNE1, KCNE2) have been demonstrated to be involved in the development of LQTS. Since this syndrome...

BACKGROUND The rate-corrected QT interval (QTc) is heritable, and the discovery of quantitative trait loci that influence the QTc would be an important step in identifying the genes responsible for life-threatening arrhythmias in the general population. We studied 66 pairs of unselected normal dizygotic (DZ) twin subjects and their parents in a sib-pair analysis. We tested for linkage of gene l...

This paper presents an adaptive equivalent consumption minimization strategy (ECMS) and a linear quadratic tracking (LQT) method for optimal power-split control of combustion engine electric machine in hybrid vehicle (HEV). The objective is to deliver demanded torque minimize fuel usage service brakes, subject constraints on actuator limits battery state charge (SOC). First, we derive function ...