The transporter associated with antigen processing (TAP) is essential for intracellular transport of protein fragments into the endoplasmic reticulum for loading of major histocompatibility complex (MHC) class I molecules. On the cell surface, these peptide-MHC complexes are monitored by cytotoxic T lymphocytes. To study the ATP hydrolysis of TAP, we developed an enrichment and reconstitution p...

INTRODUCTION Many papers have reported that TAP block provides effective postoperative analgesia, but the sole use of TAP block for surgical anesthesia has been rarely reported. CASE PRESENTATION Therefore, we presented an 80-year-old male undergoing ultrasound-guided unilateral subcostal TAP block providing surgical anesthesia for open gastrostomy. Left subcostal TAP block was performed usin...

TAP (tandem affinity purification) allows rapid and clean isolation of a tagged protein along with its interacting partners from cell lysates. Initially developed in yeast, the TAP method has subsequently been adapted to other cells and organisms. In combination with MS analysis, this method has become an indispensable tool for systematic identification of target-associated protein complexes. T...

Previously, we detected, by monoclonal antibody, three Moloney mu rine sarcoma virus (Mo-MSV)-activated intraccllular transformationassociated proteins (TAP), (P66, P63, and P60) in several Mo-MSVtransformed rat cell lines (Gian et al., Biochem. Biophys. Res. Commun., 134:1223-1230, 1986) and found the release of TAP into the extracel lular medium with a change from three intraccllular polypept...

BACKGROUND The role of vitamin E in breast cancer prevention and treatment has been widely investigated, and the different tocopherols that comprise this nutrient have been shown to have divergent associations with cancer outcome. Our previous studies have shown that α-Tocopherol-associated protein (TAP), a vitamin E binding protein, may function as a tumor suppressor-like factor in breast carc...

INTRODUCTION Transversus abdominis plane (TAP) block is a new regional analgesic technique for postoperative pain in abdominal surgery. Its efficacy is not clear, and thus it needs to be explored for its regular utilisation on prolonged period. The objective was to study the continuous local anaesthetic infusion effect on postoperative analgesia. Continuous use of TAP block as an analgesic tech...

INTRODUCTION Many countries still have unacceptably high hospitalizations and deaths from scalds from hot tap water. Prevention strategies implemented in some countries may not work in others. Legislation aimed at changing environments that are conducive to hot tap water scalds may not be effective in many situations for a number of reasons, including lack of acceptability and practicality. M...

conclusions tap-block in conjunction with laparoscopic nephrectomy did not reduce pain or opioid consumption. on the contrary, it seemed to prolong surgical time. results mean surgical time was 162 minutes in group a and 92 minutes in group b (p < 0.0001). the means of visual analogue scale (vas) were 3.05 and 1.55 in a and b groups, respectively (p = 0.001). the means of morphine consumption w...