The Ames II Salmonella mutagenicity assay procedure was used to test 71 chemicals, and the results were compared with those from the traditional Ames Salmonella test using the NTP database as the reference. All Ames II tests were performed using a fluctuation procedure in microplate format, using TAMix for the detection of base pair substitutions and TA98 to detect frameshift mutations. There w...

a Bay Area Environmental Research Institute (BAERI)/NASA Ames Research Center, Moffett Field, CA 94035, USA b Biospheric Science Branch, NASA Ames Research Center, Moffett Field, CA 94035, USA c Department of Watershed Science, Utah State University, UT 84322, USA d Department of Science and Environmental Policy, California State University at Monterey Bay/NASA Ames Research Center, Moffett Fie...

currently cancer is considered as one of the main factors of mortality globally. many chemicals in our environment can cause genetic mutations and are potentially responsible for millions of cancer-related deaths. nowadays the scientists are looking for food materials which can potenthially prevent the cancer occurrence. the purpose of this research is to examine antimutagenicity and anticancer...

روش‌های مختلفی برای زمان­‌سنجی امواج مشابه و با تحریک یکسان ارایه شده است که توجه به شرایط موج می‌­توان بهترین گزینه را انتخاب کرد. لذا هدف ما یافتن روش زمان‌سنجی جهت خروجی از حسگر UFSD زیرا می­‌خواستیم این حسگرها آشکارسازی پروتون‌ها در سیستم پروتون درمانی برای­ درمان ­تومورهای سرطانی استفاده کنیم. راستا مقایسه مختلف مثل تفکیک‌کننده کسر ثابت (CFD)، همبستگی متقابل(CC) زمان بیش آستانه (TOT)با داد...

Bacillus anthracis produces an antiphagocytic gamma-linked poly-D-glutamic acid capsule that is required for virulence. Capsule depolymerase (CapD) is a membrane-associated poly-gamma-glutamate-specific depolymerase encoded on the B. anthracis capsule plasmid, pX02, that is reported to contribute to virulence by anchoring the capsule to the peptidoglycan and partially degrading high-molecular-w...

Insulin/IGF-1 signaling involves phosphorylation/dephosphorylation of serine/threonine or tyrosine residues of the insulin receptor substrate (IRS) proteins and is associated with hormonal control of longevity determination of certain long-lived mice. The stimulation of serine phosphorylations by IGF-1 suggests there is insulin/IGF-1 crosstalk that involves the phosphorylation of the same serin...

OBJECTIVE To investigate the long-term effect of medically serious adverse medical events (AMEs) among older adults. METHODS We linked nationally representative survey and claims data from the Medicare Current Beneficiary Survey (1998-2004) with non-response files (1999-2005) and the Area Resource File, providing 12,541 beneficiaries with 428,373 person-months for analysis. Latent class analy...

This paper defines asymptotic marginal expected shortfall (AMES) for banks within a financial system and provides corresponding estimation method based on multivariate extreme value theory. The does not assume specific dependence structure among bank equity returns. Both theoretical AMES the estimator possess additive property thus can serve as tool to allocate system-wide risk individual insti...

In this nationwide study we investigated the occurrence of aminoglycoside resistance patterns and prevalence of the aminoglycoside modifying enzymes (AMEs), aac(6), ant(2) and aph(3), in clinical isolates of Acinetobacter species, E. coli, Klebsiella species and Pseudomonas species isolates from various clinical specimens. A total of 319 clinical specimens recovered from urine, blood, wound, ca...