BACKGROUND Left ventricular (LV) dilation, which is a predictor of survival in humans with chronic heart failure (CHF), is limited by a mixed endothelin ETA-ETB antagonist. Whether selective ETA receptor blockade influences LV dilation is unknown. We determined, in a rat model of CHF, the effects of the ETA receptor blocker LU 135,252 on LV remodeling. METHODS AND RESULTS Rats were subjected ...

This survey article, intended to be accessible to students, discusses results about the presence or absence of zeroes of the Bergman kernel function of a bounded domain in C. Six open problems are stated.

objective(s): the objectives of this work was to assess the benefits of the application of physiologically based pharmacokinetic (pbpk) models in patients with different neuroendocrine tumours (net) who were treatedwith lu-177 dotatate. the model utilises clinical data on biodistribution of radiolabeled peptides (rlps) obtained by whole body scintigraphy (wbs) of the patients.methods: the blood...

BACKGROUND Leishmania transmission occurs in the presence of insect saliva. Immunity to Phlebotomus papatasi or Lutzomyia longipalpis saliva or salivary components confers protection against an infection by Leishmania in the presence of the homologous saliva. However, immunization with Lutzomyia intermedia saliva did not protect mice against Leishmania braziliensis plus Lu. intermedia saliva. I...

Studies were undertaken on the phlebotomines in the municipalities of Bujari, Xapuri and Rio Branco in the state of Acre. The abundance of species on the ground and in the tree canopy was estimated by Standardized Index of Species Abundance. Of the 52 species identified, Lutzomyia (N.) antunesi, Lutzomyia (N.) whitmani, Lutzomyia (P.) davisi, Lutzomyia migonei, Lutzomyia (N.) umbratilis, Lutzom...

BACKGROUND Previous works showed that immunization with saliva from Lutzomyia intermedia, a vector of Leishmania braziliensis, does not protect against experimental infection. However, L. braziliensis is also transmitted by Lutzomyia whitmani, a sand fly species closely related to Lu. intermedia. Herein we describe the immune response following immunization with Lu. whitmani saliva and the outc...

The invention and use of mobile commerce (m-commerce) technology have progressed tremendously in recent years. In small to medium-sized enterprises (SMEs), the decision of business-to-business (b2b) mcommerce is a multi-criterion decision analysis problem which involves both qualitative and quantitative factors, and its evaluation may be based on imprecise information or uncertain data. Further...

Systems of linear equations can be represented by matrix equations of the form A~x = ~b. LU Factorization is a method for solving systems in this form by transforming the matrix A into a form that makes backwards and forward susbstitution feasible. A common algorithm for LU factorization is Gaussian elimination, which I used for my serial and parallel implementations. I investigated using async...

Article history: Received 20 February 2015 Received in revised form 17 April 2016 Accepted 29 April 2016 Available online 5 May 2016 Communicated by Thomas Strohmer