In a tractable model for cell invasion, the Caenorhabditis elegans anchor cell migrates through basement membranes towards a polarity cue provided by netrin. A new study reveals that the anchor cell polarity network can break symmetry and oscillate in the absence of netrin, suggesting the presence of interlinked positive and negative feedback loops, which are common in polarity pathways.

STUDY OBJECTIVE To assess the secondary health impacts of a traffic calming scheme on a community. METHODS Prospective cohort study of a randomly selected sample of the local community using postal questionnaires and pedestrian counts on the affected road six months before and six months after the implementation of the scheme. The setting was a community in which a traffic calming scheme was ...

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Declarative networking is an approach where distributed computations are modeled and programmed using declarative formalisms based on extensions of Datalog. On a logical level, programs (queries) are specified over a global schema and are computed by multiple distributed computing nodes over which the input database is partitioned. These nodes can perform local computations and communicate asyn...

This paper describes a context aware pervasive calm medication reminder system. The system aims at improving the anticoagulant treated patient’s medication adherence based on context awareness. By using advanced sensor technology to register the user context, the system reminds the patient to take the medication timely. The system prototype was tested and evaluated by a patient, and was reporte...

The promise of calm computing,1 a concept introduced by Mark Weiser more than 20 years ago, has been mostly realized today. For instance, as an end user, you expect to interact during your daily routine with multitude sophisticated services and applications without being aware their technical implementation. All need is smartphone always-on Internet connection.