(CBA x B6)F1 (Iak x Iab) T cells were activated to sheep erythrocytes in irradiated F1 mice in the presence of various monoclonal anti-Ia reagents and then tested for their capacity to collaborate with B cells from B10.BR (I-Ak, I-Ek) (kk), B10.A(4R) (kb), and B10 (bb) mice. Anti-I-Ak antibodies blocked the generation of help for B10.A(4R) B cells, but not B10.BR or B10 B cells. An anti-I-Ab an...

The importance of architectural knowledge (AK) management for software development has been highlighted over the past ten years, where a significant amount of research has been done. Since the first systems using design rationale in the seventies and eighties to the more modern approaches using AK for designing software architectures, a variety of models, approaches, and research tools have lev...

Arginine kinase (AK) was isolated from the longitudinal muscle of the sea cucumber Stichopus japonicus. Unlike the monomeric 40 kDa AKs from molluscs and arthropods, but like the cytoplasmic isoenzymes of vertebrate creatine kinase (CK), the Stichopus enzyme was dimeric. To explore the evolutionary origin of the dimeric AK, we determined its cDNA-derived amino acid sequence of 370 residues. A c...

This study investigates the potential of the alpha CD3-induced killer cells for use in adoptive immunotherapy of tumor growth. The alpha CD3-induced, activated, killer cells (CD3-AK) were generated in DBA/2 (H-2d) splenocytes by preactivation with alpha CD3 and were then cultured in the presence (CD3-AK [alpha CD3+]) or absence (CD3-AK [alpha CD3-]) of alpha CD3. The conventional lymphokine-act...

The aim of this study was to compare the nephrotoxic potential of amikacin (AK) and gentamicin (GM) in patients with normal baseline renal function. This study was a 1-year, non-interventional prospective study of patients administered either GM or AK. The study was carried out at the internal medicine department of Al-Watani governmental study. Nephrotoxicity was defined as a serum creatinine ...

We define Ak-moves for embeddings of a finite graph into the 3-sphere for each natural number k. Let Ak-equivalence denote an equivalence relation generated by Ak-moves and ambient isotopy. Ak-equivalence implies Ak−1-equivalence. Let F be an Ak−1-equivalence class of the embeddings of a finite graph into the 3-sphere. Let G be the quotient set of F under Ak-equivalence. We show that the set G ...

Let a1, a2, . . . , ak be relatively prime, positive integers arranged in increasing order. Let Γ denote the positive integers in the set { a1x1 + a2x2 + · · ·+ akxk : xj ≥ 0 }. Let S(a1, a2, . . . , ak) . = {n / ∈ Γ : n+ Γ ⊆ Γ }. We determine S(a1, a2, . . . , ak) in the case where the aj’s are in arithmetic progression. In particular, this determines g(a1, a2, . . . , ak) in this particular c...

Aspartate kinase (AK) and homoserine dehydrogenase (HSDH) are enzymes in the aspartate-derived amino acid biosynthetic pathway. Recent biochemical evidence indicates that an AK-HSDH bifunctional enzyme exists in maize (Zea mays 1.). In this report, we characterize three genes that encode subunits of AK-HSDH. Two cDNAs, pAKHSDHl and pAKHSDH2, containing the fullcoding sequence, and one partial c...

In this chapter we report case studies in two companies to investigate how the use of file-based and ontology-based documentation influences AK retrieval (RQ4). A common approach to SA documentation in industry projects is the use of filebased documents. This approach offers a single-dimensional arrangement of the AK. AK retrieval from file-based documentation is efficient if the organisation o...

We call a sum a1 + a2 + · · ·+ ak a partition of n of length k if a1, a2, . . . , ak and n are positive integers such that a1 ≤ a2 ≤ · · · ≤ ak and n = a1 + a2 + · · ·+ ak. For i = 1, 2, . . . , k, we call ai the i-th part of the sum a1 + a2 + · · ·+ ak. Let Pn,k be the set of all partitions of n of length k. We say that two partitions a1 + a2 + · · · + ak and b1 + b2 + · · ·+ bk strongly inter...