Employment or Leadership: None declared. Consultant or Advisory Role: None declared. Stock Ownership: None declared. Honoraria: None declared. Research Funding: R. Ensenauer, German Federal Ministry of Education and Research (BMBF) grant no. 0315088; J. Gmach, German Federal Ministry of Education and Research (BMBF) grant no. 0315088; Ina Nehring, German Federal Ministry of Education and Resear...

conclusions our results demonstrated that the extract of ob could induce anxiolytic effect in rats after 1 week oral administration. the effect of ob was not induced through changes in motor activity. further investigations are necessary for pharmacological providing of ob and better understanding of its anxiolytic properties and neurobiological mechanisms. results the results showed that after...

putative activity of hydroalcoholic and aqueous infusion extracts of echium amoenum l. was investigated in mice using the rotarod model of motor coordination and the elevated plus maze model of anxiety. the extracts were administered intraperitonealy (i.p.) once, one hour before performing the tests. preliminary phytochemical study of the plant, with standard procedures, showed that it contains...

introduction: sildenafil, a phosphodiesterase-5 (pde5) inhibitor, may have various effects on the central nervous system via the nitric oxide (no)-cyclic guanosine monophosphate (cgmp) pathway. preclinical studies have shown the controversial effect of sildenafil on anxiety-like behavior in animals. this study was undertaken to investigate the acute effect of sildenafil on anxiety-like behavior...

Most office buildings in the warm-humid sub-Saharan countries experience high cooling load because of the predominant use of sandcrete blocks which are of low thermal mass in construction and extensive use of glazing. Relatively, low night-time temperatures are not harnessed in cooling buildings because office openings remain closed after work hours. An optimization was performed through a sens...

We evaluated four techniques for controlling focus+context screens. We compared an egocentric versus exocentric View mixed with whether the display on the focus screen moves in the same (paper mapping) versus opposite (scroll mapping) direction as input force. Our results show that (i) View had little effect, (ii) users almost always allocated attention to the context screen when controlling th...

The aim of this research, is to provide empirical data to either support or challenge the view that subculture has an impact on how sex appeal in advertising is perceived. It looks at young females of two specific British subcultural groups, Anglo-Saxon and Asian-Islamic British. It reveals that there are differences in the perception of sex appeal, since the Asian-Islamic British have a rather...

XMAP215 is a microtubule plus-end binding protein implicated in modulating microtubule dynamics. In this issue, Brouhard et al. (2008) propose a new mechanism to explain how XMAP215 promotes microtubule growth. They report that XMAP215 moves with the growing microtubule plus ends where it catalyzes the addition of tubulin subunits.