PURPOSE Intramyocardial hemorrhage and area at risk are both prognostic markers in acute myocardial infarction (AMI). Myocardial T2 and T2 * mapping have been used to detect such tissue changes at 1.5T but these techniques are challenging at 3.0T due to additional susceptibility variation. We studied T2 and T2 * myocardial mapping techniques at 3.0T on a system employing B1 shimming and compare...

Background: Cardiac complications due to iron overload are the most common cause of death in patients with thalassemia major. The aim of this study was to compare iron chelation effects of deferoxamine, deferasirox, and combination of deferoxamine and deferiprone on cardiac and liver iron load measured by T2* MRI. Methods: In this study, 108 patients with thalassemia major aged over 10 years...

Introduction: Ultrashort echo time (UTE) MRI requires specialized pulse sequences to overcome the short T2 relaxation of the MR signal encountered in tissues such as ligaments, tendon or cortical bone. Imaging short T2 tissues is achieved in UTE by acquiring the Free Induction Decay (FID) of the MR signal as soon after the end of the RF excitation pulse as possible. This is typically accomplish...

Background: Iron-mediated cardiomyopathy is the main complication of thalassemia major (TM) patients. Therefore, there is an important clinical need in the early diagnosis and risk stratification of patients. The aim of this study was to evaluate the efficacy of tissue doppler imaging (TDI) to study cardiac iron overload in patients with TM using T2* magnetic resonance (MR) as the gold-standard...

purpose t1wi (t1 weighted image) was acquired in order to grade bone fusion following the studies by fifa (federation internationale de football associations). research using images other than t1wi has not been reported. the aim of this study is to evaluate the grade of epiphyseal fusion by t2* weighted images (t2*wi) and to investigate new findings on t2*wi as compared with t1wi. methods a tot...

background: in recent years, the success in management of thalassemic patients, has allowed for some previously unrecognized complications including renal abnormalities to emerge. this prospective study aimed to investigate kidney iron overload by means of mri t2* and also renal function based on laboratory tests for early markers of glomerular and tubular dysfunction among adult iranian transf...