In this paper we investigate external phone duration models (PDMs) for improving the quality of synthetic speech in hidden Markov model (HMM)-based speech synthesis. Support Vector Regression (SVR) and Multilayer Perceptron (MLP) were used for this task. SVR and MLP PDMs were compared with the explicit duration modelling of hidden semi-Markov models (HSMMs). Experiments done on an American Engl...

We have isolated the Xenopus homologue of Muscle LIM protein (MLP, CRP3) and examined its expression during early embryonic development. MLP is only expressed in the differentiated heart during early development and is expressed in a subset of other striated muscles during later stages. There is no MLP expression during primary myogenesis in the somites, although it is found in adult skeletal m...

This is the first report, to our knowledge, to reveal important factors by which members of the Cucurbitaceae family, such as cucumber (Cucumis sativus), watermelon (Citrullus lanatus), melon (Cucumis melo), pumpkin (Cucurbita pepo), squash (C. pepo), and zucchini (C. pepo), are selectively polluted with highly toxic hydrophobic contaminants, including organochlorine insecticides and dioxins. X...

PURPOSE A lipid-based prodrug of mitomycin C [MMC; 2,3-(distearoyloxy)propane-1-dithio-4'-benzyloxycarbonyl-MMC] was designed for liposome formulation. The purpose of this study was to examine the in vitro cytotoxicity, pharmacokinetics, in vivo toxicity, and in vivo antitumor activity of this new lipid-based prodrug formulated in polyethylene glycol-coated (pegylated) liposomes. EXPERIMENTAL...

Axillary Lymph Node (ALN) status is an extremely important factor to assess metastatic breast cancer. Surgical operations which may be necessary and cause some adverse effects are performed in determination ALN status. The purpose of this study is to predict ALN status by means of selecting breast cancer patient’s basic clinical and histological feature(s) that can be obtained in each hospital....

In mouse melanocytes, myosin Va is recruited onto the surface of melanosomes by a receptor complex containing Rab27a that is present in the melanosome membrane and melanophilin (Mlp), which links myosin Va to Rab27a. In this study, we show that Mlp is also a microtubule plus end-tracking protein or +TIP. Moreover, myosin Va tracks the plus end in a Mlp-dependent manner. Data showing that overex...

In this paper a new scheme of feature ranking and hence feature selection using a Multilayer Perceptron (MLP) Network has been proposed. The novelty of the proposed MLP-based scheme and its difference from another MLP-based feature ranking scheme have been analyzed. In addition we have modified an existing feature ranking/selection scheme based on fuzzy entropy. Empirical investigations show th...

The paper presents an S-Transform based multilayer perceptron neural network (MLP) classifier for the identification of power quality (PQ) disturbances.The proposed method is used to extract the three input features (Standard deviation, peak value and variances) from the distorted voltage waveforms simulated using parametric equations. The features extracted through S-transform are trained by a...

Systems (DEMS) is proposed. This MLP algorithm uses a gradient metric based on hardware-software cost and performance as the core metric for selection of optimal partitions and consists of three nested levels. The innermost level is a simple binary search that allows quick evaluations of a large number of possible partitions. The middle level iterates over different possible allocations of proc...

The main goal of this paper is to compare the performance which can be achieved by five different approaches analyzing their applications’ potentiality on real world paradigms. We compare the performance obtained with (1) Multi-network RBF/LVQ structure (2) Discrete Hidden Markov Models (HMM) (3) Hybrid HMM/MLP system using a Multi LayerPerceptron (MLP) to estimate the HMM emission probabilitie...