AIM The prognosis of patients with ovarian cancer depends on stage, histological type, age, presence of ascites, performance status and debulking surgery. Complete cytoreductive surgery is the most important prognostic factor. We investigated the suitability of Ca 125 as a prognostic factor in patients with ovarian cancer at various. PATIENTS AND METHODS In a retrospective analysis, the Ca 12...

BACKGROUND High carbohydrate antigen 125 (CA-125) level was reported to be associated with some cardiac dysfunctions, such as chronic heart failure, but the relationship between CA-125 level and coronary heart disease (CHD) risk remains unclear. The aim of this study was to explore the potential association in a Chinese older population. METHODS In a population-based case-control study conduc...

Tumor markers could increase in both tuberculous peritonitis and peritonitis carcinomatosa, confusing the differentiation of these diseases. This study aimed to better understand the extent of elevation and diagnostic efficacies of carbohydrate antigen 125 (CA 125), carcinoembryonic antigen (CEA) and combinative use of them in tuberculous peritonitis and peritonitis carcinomatosa. Of 2998 patie...

A novel strategy for immunoassay and the preparation of reagentless immunosensors was proposed. This strategy was based on the immobilization of antigen and the direct electrochemistry of horseradish peroxidase (HRP) that was labeled to an antibody. A reagentless immunosensor for carcinoma antigen-125 (CA 125) determination was developed. The immunosensor was prepared by immobilizing CA 125 wit...

BACKGROUND Cancer antigen 125 (CA-125) is a glycoprotein biomarker that is used in women with pelvic masses such as endometriosis and maybe is useful in practice of patients suspicious to endometriosis. OBJECTIVE The aim of this study was to evaluate the association between preoperative serum CA-125 levels and clinic pathological characteristic in women with endometriosis, and find out the be...

BACKGROUND The mortality and morbidity associated with oral squamous cell carcinoma (OSCC) can be greatly reduced if tumor markers which can detect OSCC at an early stage are available. The use of saliva as an alternative to blood could provide a substantial advantage in sampling convenience. Cancer antigen 125 (CA 125) is a tumor-associated antigen found to be increased in epithelial tumors li...

Gold nanowires with of designed length on a solid substrate have been proven as an efficiently immobilized affinity support for the detection of carcinoma antigen 125 (CA 125) in this study. The presence of gold nanowires provides a well-defined three-dimensional structure, and greatly amplifies the coverage of the anti-CA 125 protein on the probe surface. Moreover, the amount of anti-CA 125 va...

Human placental alkaline phosphatase (hPLAP; EC 3.1.3.1), cancer antigen 125 (CA 125), and carcinoembryonic antigen (CEA) were determined in sera of patients with malignant and nonmalignant disorders. For CA 125 we used two different commercial assay systems, based on the same monoclonal antibody. hPLAP had the same sensitivity (20%) as CA 125 for detecting non-ovarian neoplasia, whereas that o...

Two hundred eighty-eight serum specimens from 144 asymptomatic menopausal women were assayed two times each for CA 125. The specimens were randomly assigned to sixteen CA 125 kits. Our purpose was to quantitate the biological variability and the assay variability that occurs at low levels of this tumor marker. All of the subjects had CA 125 values less than 35 units/ml. The total error from all...

OBJECTIVE To evaluate the correlation between Cancer Antigen-25 (CA-125) levels with the amount of ascites in patients with liver cirrhosis. STUDY DESIGN Observational, analytical study. PLACE AND DURATION OF STUDY Shifa International Hospital, Islamabad, from March 2012 to February 2013. METHODOLOGY A total of 130 patients with liver cirrhosis (with and without ascites) had serum CA-125 ...