Lieutenant Colonel Robert Likeman served as Commanding Officer of the 9th Field Ambulance and the 11th Brigade Administrative Support Battalion, and was Senior Medical Officer of the 11th Brigade from 1964 to 2001. He has had operational deployments to Rwanda and East Timor. In his civilian life as a Specialist in Obstetrics and Gynaecology he has lived and worked in the Middle East, Papua New ...

Army’s notorious Unit 731 was apparently unconcerned by the dilemma confronting him. Indeed, he conveniently linked the goals of medical research with the military mission, despite his unit’s involvement in human vivisection, biological weapons testing, and freezing experiments. Sadly, the Japanese Army was not alone in its corruption of the Hippocratic Oath. Perhaps more infamous was the state...

BACKGROUND Alternate-day-fasting (ADF) has been proposed as an effective dieting method. Studies have found that it also can increase life span in rodents, and reduce inflammation in humans. The aim of this paper was to systematically review the efficacy of ADF compared to very-low-calorie dieting (VLCD) in terms of weight loss, and reduction of fat mass and fat-free mass. METHODS Systematic ...

BACKGROUND Alternate day fasting (ADF) is a novel diet therapy that reduces body weight, but its effect on bone health remains unknown. OBJECTIVE This study examined the impact of ADF versus traditional daily calorie restriction (CR) on markers of bone metabolism in a 6-month randomized controlled trial. METHODS Overweight and obese subjects (n = 100) were randomized to 1 of 3 groups for 6 ...

Chemotherapy for adult T-cell leukemia (ATL) has been reported to fail to induce complete remission because of drug resistance in most patients. We have examined the expression of an ATL-derived factor (ADF)/thioredoxin in relation to resistance to adriamycin (ADM) in various T-cell leukemia cell lines including ATL cell lines. Immunoblot analysis demonstrated that ATL cell lines expressed ADF/...

Based mostly on the results of in vitro experiments, ADF (actin-depolymerizing factor) proteins are thought to be key modulators of the dynamic organization of the actin cytoskeleton. The few studies concerned with the in vivo function of ADF proteins that have been reported to date were performed almost exclusively using single-cell systems and have failed to produce consistent results. To inv...

Stabilization of actin filaments is critical for supporting actomyosin-based contractility and for maintaining stable cellular structures. Tropomyosin is a well-characterized ubiquitous actin stabilizer that inhibits ADF/cofilin-dependent actin depolymerization. Here, we show that UNC-87, a calponin-related Caenorhabditis elegans protein with seven calponin-like repeats, competes with ADF/cofil...

The Australian Defence Force (ADF) has used mefloquine for malaria chemoprophylaxis since 1990. Mefloquine has been found to be a plausible cause of a chronic central nervous system toxicity syndrome and a confounding factor in the diagnosis of existing neuropsychiatric illnesses prevalent in the ADF such as posttraumatic stress disorder and traumatic brain injury. Overall health risks appear t...

Primary aortoduodenal fistula (ADF) is a rare but morbid diagnosis. Here, we present the case of a patient with a primary ADF that resulted in mortality. Despite multiple attempts at radiographic and endoscopic diagnosis, the fistula did not declare itself until the patient exsanguinated. Given the morbidity associated with ADF and the imperfection of associated diagnostic studies, a high index...

A lattice-ladder adaptive decorrelation filtering (ADF) algorithm is proposed with the aim of developing a more efficient co-channel speech separation system. It is shown that based on the joint forward and backward linear predictions, a lattice-ladder structure can be derived for ADF. Experimental results show that the proposed algorithm is effective in reducing cross-interference between co-c...