Submit Manuscript | http://medcraveonline.com Abbreviations: LCPUFAs: Long-Chain Polyunsaturated Fatty Acids; ω6: Omega-6 Family; GLA: γ-Linolenic Acid; AA: Arachidonic Acid; ω3: Omega-3 Family; EPA: Eicosapentaenoic Acid; DHA: Docosahexaenoic Acid; AL: Linoleic Acid; AAL: Alpha-Linolenic Acids; vitamin A: Beta-Carotene; vitamin K: Phylloquinone; vitamin E: Alpha-Tocopherol; B1: Thiamine; B2: R...

BACKGROUND During heart failure (HF), cardiac metabolic substrate preference changes from fatty acid (FA) toward glucose oxidation. This change may cause progression toward heart failure. We hypothesize that a diet rich in FAs may prevent this process, and that dietary ω3-FAs have an added antiarrhythmic effect based on action potential (AP) shortening in animals with HF. METHODS AND RESULTS ...

Purpose: Suitable ratio of essential fatty acids has an important role in maintaining good health. There is no pure oil with an ideal fatty acid composition and oxidative stability. The main goal of the present study was to evaluate the physical, chemical and nutritional properties of oil obtained by blending flaxseed oil as a rich source of ω3 fatty acids with sesame and olive oils. Methods: T...

Submit Manuscript | http://medcraveonline.com Abbreviations: LCPUFAs: Long-Chain Polyunsaturated Fatty Acids; ω6: Omega-6 Family; GLA: γ-Linolenic Acid; AA: Arachidonic Acid; ω3: Omega-3 Family; EPA: Eicosapentaenoic Acid; DHA: Docosahexaenoic Acid; AL: Linoleic Acid; AAL: Alpha-Linolenic Acids; vitamin A: Beta-Carotene; vitamin K: Phylloquinone; vitamin E: Alpha-Tocopherol; B1: Thiamine; B2: R...

Inflammation, oxidative stress, and uncontrolled cell proliferation are common key features of chronic inflammatory diseases, such as atherosclerosis and cancer. ω3 polyunsaturated fatty acids (PUFAs; also known as omega3 fatty acids or fish oil) have beneficial effects against inflammation upon dietary consumption. However, these effects cannot be fully exploited unless diets are enriched with...

Omega-3 polyunsaturated fatty acids (ω3-PUFAs), including docosahexaenoic acid (DHA), have been shown to exert anticancer effects by inducing apoptotic cell death. However, the mechanism for DHA-induced cell death in lung cancer is not fully understood. Here, we show that DHA induces apoptosis in two human EGFR mutant non-small cell lung cancer (NSCLC) cell lines, and that DHA-induced cell deat...

Abstract Several methods are available for elongation of fatty acid acyl chains. The present paper describes adaptation to the field a previously published protocol manganese‐based Wurtz type coupling alkyl bromides. 22‐Bromo‐3( Z ),6( ),9( ),12( ),15( ),18( )‐docosahexaene, easily prepared from 4( ),7( ),10( ),13( ),16( ),19( )‐docosahexaenoic acid, was coupled homologous ω‐bromoesters by stir...

Cardiovascular disease (CVD) remains one of the major causes of death and disability worldwide. In addition to drug treatment, nutritional interventions or supplementations are becoming a health strategy for CVD prevention. Phytosterols (PhyS) are natural components that have been shown to reduce cholesterol levels; while poly-unsaturated fatty acids (PUFA), mainly omega-3 (ω3) fatty acids, hav...