Purpose: Germ cell tumors (GCT) of the testis are highly curable, but those patients who are refractory to cisplatin (CDDP)-based combination chemotherapy have a poor prognosis. Therefore, identifying new alternatives for treatment remains a priority. Several studies support an important role for angiogenesis in GCTs, suggesting that antiangiogenic treatment might be a good alternative. Sunitin...

A previously healthy, 7-mo-old male infant presented with a 3-mo history of pubic hair. He was a healthy, term newborn who was born to nonconsanguineous parents, and had appropriate weight and length. Physical examination revealed thick and long pubic hair on the scrotum, without hyperpigmentation or enlargement of the penis (Fig. 1a). No other signs of virilization or secondary sexual developm...

Cell-cell fusion is an essential event during life. Throughout human pregnancy, the syncytiotrophoblast (STB) layer of the placenta is formed by continuous fusion of the underlying villous cytotrophoblasts, thus maintaining placental functionality. Defects in this process are associated with pathologies like pre-eclampsia and intrauterine growth restriction. Krüppel-like factor 6 (KLF6) is a tr...

BACKGROUND Human hydatid disease is caused by echinococcus granulosus and has a global distribution. It mainly affects the liver, but can involve other organs. In this paper, we present a case of a primary hydatid cyst of the fallopian tube. CASE PRESENTATION A 69-year-old (gravida 16, para 16 woman) with abdominal pain and urinary frequency was presented to the Gynecology Clinic of Imam Khom...

Preimplantation genetic diagnosis was carried out for embryonic analysis in a patient with multiple endocrine neoplasia type 1 (MEN1). This is a rare autosomal-dominant cancer syndrome and the patients with MEN1 are characterized by the occurrence of tumors in multiple endocrine tissues, associated with germline and somatic inactivating mutations in the MEN1 gene. This case report documents a s...

Placental polyp is a organized mass of retained bits of placental tissue following delivery, which is hyalinized during their prolonged retention. It is a rare entity, histologically composed of necrotic and hyalinized chorionic villi. These placental masses present within days to weeks following an abortion or delivery of a term placenta. The usual clinical presentations are abnormal uterine b...

Mục tiêu: Đánh giá kết quả điều trị chửa ngoài tử cung tại Bệnh viện Quân y 103 trong 2 năm (2020-2022). Đối tượng và phương pháp: nghiên cứu tiến cắt ngang trên 111 bệnh nhân nội trú Y từ tháng 6/2020 đến 5/2022. Kết quả: Tuổi trung bình là 32,68 ±5,55 tuổi, 25-35 tuổi chiếm 54%, 74,78% được bằng phẫu thuật soi, 27,72% mổ mở, còn lại khoa methotrexat (MTX) (4,5%). 1-3 liều MTX, 65,22% dùng 1 M...