نتایج جستجو برای: zebra fish
تعداد نتایج: 107506 فیلتر نتایج به سال:
The Hedgehog (Hh) signaling pathway plays an integral role in the patterning and development of diverse structures in the vertebrate embryo. Aberrations in Hh signaling are associated with a range of developmental defects including failure of interhemispheric division of the embryonic forebrain as well as midline facial dysmorphia including cleft lip/palate and cyclopia, collectively termed hol...
Apurinic/apyrimidinic endonuclease 1, a key enzyme in repairing abasic sites in DNA, is an embryonic lethal in mice. We are examining its role in embryogenesis in zebra fish. Zebra fish contain two genomic copies (zfAPEX1a and zfAPEX1b) with identical coding sequences. zfAPEX1b lacks introns. Recombinant protein (ZAP1) is highly homologous with and has the same enzymatic properties as its human...
Pax6 is a developmental regulatory gene that plays a key role in the development of the embryonic brain, eye, and retina. This gene is also expressed in discrete groups of neurons within the adult brain. In this study, antibodies raised against a fusion protein from a zebra fish pax6 cDNA were used to investigate the expression of the pax6 gene in the mature, growing, and regenerating retina of...
BACKGROUND Ginsenoside-Rg3, the pharmacologically active component of red ginseng, has been found to inhibit tumor growth, invasion, metastasis, and angiogenesis in various cancer models. Previously, we found that 20(R)-ginsenoside-Rg3 (Rg3) could inhibit angiogenesis. Since microRNAs (miRNAs) have been shown to affect many biological processes, they might play an important role in ginsenoside-...
Diamond-Blackfan anemia (DBA) is a cancer-prone inherited bone marrow failure syndrome. Approximately half of DBA patients have a germ-line mutation in a ribosomal protein gene. We used whole-exome sequencing to identify disease-causing genes in 2 large DBA families. After filtering, 1 nonsynonymous mutation (p.I31F) in the ribosomal protein S29 (RPS29[AUQ1]) gene was present in all 5 DBA-affec...
Tribenuron metil tarımda çok yıllık dikotları kontrol etmek için kullanılan herbisittir. Sucul ekosistemlere yeraltı suyu yoluyla erişebilir ve sucul yaşamı etkileyebilir. Zebra balığı (Danio rerio Hamilton, 1822), kolay üreme kapasitesine şeffaf embriyolara sahip olan bu yüzden bilimsel çalışmalarda sıkça tercih edilen bir omurgalı modelidir. Bu çalışmada tribenuron zebra balıkları üzerinde 12...
Danio rerio is one of the most beautiful ornamental fish living in fresh water and tropical water having a lot of fans in our country. This study aimed at investigating the effect of flaked diet with spirulina microalga feeding on growth and survival rates of Danio rerio in Mahshahr, south of Iran in 2014. Three hundred and sixty zebra fish have been purchased and were randomly distributed amo...
Songbird species (order Passeriformes, suborder Oscines) are important models in various experimental fields spanning behavioural genomics to neurobiology. Although the genomes of some songbird species were sequenced recently, the chromosomal organization of these species is mostly unknown. Here we focused on the two most studied songbird species in neuroscience, the zebra finch (Taeniopygia gu...
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