Background: The analgesic paracetamol causes a potentially fatal, centrilobular hepatic necrosis when taken in misuse and overdose. This research aimed to evaluate the protective effects of methanolic extract of Zataria Multiflora Boiss (Z. Multiflora) against hepatic damage induced by paracetamol-induced hepatotoxicity in male Wistar rats. Methods: for this purpose, paracetamol was administrat...

zataria multiflora boiss is used in traditional folk remedies as antiseptic, analgesic, carminative, anthelmintic medication. the main components of zataria multiflora are phenolic compounds such as thymol and carvacrol. the aim of this study was developed a simple and rapid method for determination of the thymol in different extracts of zataria multiflora by hplc method. the dried aerial parts...

Background: This research aimed to evaluate the protective effects of methanolic extract of Zataria Multiflora Boiss (Z. Multiflora) against hepatic damage induced by cisplatin in male Wistar rats. Methods: Hepatotoxicity was induced in Wistar male rats by a single intraperitoneal administration of cisplatin, 7 g/ kg body weight. A methanolic extract of Z. Multiflora was administered orally at ...

we studied the antioxidant activities of the essential oils of zataria multiflora boiss. (zeo) and bunium persicum (boiss.) b. fedtsch (beo) in mixed form on linseed oil using (dpph•), ­(­abts•+), h2o2 scavenging, and reducing power assays. after calculation of ic50 for zeo and beo separately, interactions of the essential oils were investigated at the form of mixture and the results were given...

Poultry meat is one of the perishable foods. The growth of pathogenic microorganisms may occur in chicken meat during refrigerated storage. Microbial growth causes serious hazard in food safety consumer. The aim of this study was to compare antimicrobial properties of Thymus vulgaris (TEO) and Zataria multiflora essential oil (ZEO) and the effect of carboxymethyl cellulose (CMC) films containin...

The stimulatory effect of Zataria multiflora Boiss (Labiatae) and carvacrol on β-adrenoceptors was examined on guinea pig trachea. The effects of three concentrations of aqueous-ethanolic extract, carvacrol, and propranolol (β-receptor antagonist) on β-adrenoceptors were tested in nonincubated (group 1, n = 8) and incubated tracheal chains with 1 μM chlorpheniramine (histamine H1 receptor antag...

The effect of aqueous-ethanolic extract of Zataria multiflora Boiss (Labiatae), on βadrenoceptors was examined on tracheal chains of guinea pigs. The effects of three concentrations of aqueous-ethanolic extract (0.05, 0.1 and 0.2 mg/mL), 10 nM propranolol, and saline on β-adrenoceptors were tested (n=8). The results showed clear leftward shifts in isoprenaline curves obtained in the presence of...

The green synthesis of metallic nanoparticles is an active research area in nanotechnology. In the present study, antioxidant potential, total reducing capacity and silver nanoparticles' (Ag NPs) synthetic potential of methanolic leaf extracts of seven plant species were evaluated and compared. Antioxidant capacity, expressed as µmol Trolox equivalents g-1 DW (µmol TE g-1 DW), ranged from 116.0...