نتایج جستجو برای: yttrium microspheres

تعداد نتایج: 15959  

Journal: :Journal of hepatology 2013
Rita Golfieri Josè Ignacio Bilbao Livio Carpanese Roberto Cianni Daniele Gasparini Samer Ezziddin Philipp Marius Paprottka Francesco Fiore Alberta Cappelli Macarena Rodriguez Giuseppe Maria Ettorre Adelchi Saltarelli Onelio Geatti Hojjat Ahmadzadehfar Alexander R Haug Francesco Izzo Emanuela Giampalma Bruno Sangro Giuseppe Pizzi Ermanno Notarianni Alessandro Vit Kai Wilhelm Tobias F Jakobs Secondo Lastoria

BACKGROUND & AIMS The European Network on Radioembolization with Yttrium-90 resin microspheres study group (ENRY) conducted a retrospective study to evaluate the outcomes among elderly (≥ 70 years) and younger patients (<70 years) with unresectable hepatocellular carcinoma (HCC) who received radioembolization at 8 European centers. METHODS Patients with confirmed diagnosis of unresectable HCC...

Journal: :International journal of radiation oncology, biology, physics 2012
Wan-Yee Lau Andrew S Kennedy Yun Hwan Kim Hee Kit Lai Rheun-Chuan Lee Thomas W T Leung Ching-Sheng Liu Riad Salem Bruno Sangro Borys Shuter Shih-Chang Wang

PURPOSE Selective internal radiotherapy (SIRT) with yttrium-90 ((90)Y) resin microspheres can improve the clinical outcomes for selected patients with inoperable liver cancer. This technique involves intra-arterial delivery of β-emitting microspheres into hepatocellular carcinomas or liver metastases while sparing uninvolved structures. Its unique mode of action, including both (90)Y brachyther...

2017
Hyo-Cheol Kim

Transarterial radioembolization (TARE) with yttrium 90 (90Y), an intra-arterial procedure performed by interventional radiologists, has begun being utilized in managing hepatocellular carcinoma (HCC) in Korea. There are two available TARE products: glass and resin microspheres with different physical characteristics. All patients undergoing TARE must be assessed with clinical examination and la...

2013
Pavel Singh Gopinathan Anil

Transarterial radioembolization (TARE) with yttrium 90 microspheres is an increasingly popular therapy for both primary and secondary liver malignancies. TARE entails delivery of β-particle brachytherapy and embolization of the tumor vasculature. The consequent biological sequelae are distinct from those of other transarterial therapies for liver tumors, as reflected in the often baffling post-...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 1999
E D Yorke A Jackson R A Fox B W Wessels B N Gray

Normal liver complications have not been observed in Y-90 microsphere therapy of hepatic tumors [selective internal radiation (SIR)], despite clinical studies reporting estimated absorbed doses to normal liver between 100 and 150 Gy. The purpose of the study was to see whether predictions of normal tissue complication probability (NTCP) models for liver based on clinical data from external beam...

Journal: :Liver cancer 2015
Julien Edeline Marine Gilabert Etienne Garin Eveline Boucher Jean-Luc Raoul

Yttrium-90 (Y90) radioembolization is an emerging strategy to treat liver malignancies, and clinical data supporting its use have accumulated in recent years. Y90-radioembolization has shown clinical effectiveness in intermediate and advanced hepatocellular carcinoma, with a favorable safety profile. Retrospective data show similar levels of effectiveness to transarterial chemoembolization in i...

2017
Katarina Sjögreen Gleisner Emiliano Spezi Pavel Solny Pablo Minguez Gabina Francesco Cicone Caroline Stokke Carlo Chiesa Maria Paphiti Boudewijn Brans Mattias Sandström Jill Tipping Mark Konijnenberg Glenn Flux

BACKGROUND Currently, the implementation of dosimetry in molecular radiotherapy (MRT) is not well investigated, and in view of the Council Directive (2013/59/Euratom), there is a need to understand the current availability of dosimetry-based MRT in clinical practice and research studies. The aim of this study was to assess the current practice of MRT and dosimetry across European countries. M...

Journal: :Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2011
Vanessa L Gates Abdulredha A H Esmail Karen Marshall Stewart Spies Riad Salem

UNLABELLED Radioembolization with 90Y microspheres represents a novel transarterial radiation treatment for liver tumors. The purpose of this pilot study was to evaluate the findings of postimplantation PET/CT of 90Y glass microspheres. METHODS Three patients with hepatocellular carcinoma and 2 patients with liver metastases (1 neuroendocrine, 1 colorectal) underwent PET/CT after radioemboliz...

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