Award Number: W81XWH-08-1-0108 TITLE: The role of eIF4E activity in breast cancer PRINCIPAL INVESTIGATOR: Thomas A Hughes CONTRACTING ORGANIZATION: University of Leeds Leeds LS2 9-0000 REPORT DATE: August 2010 TYPE OF REPORT: Annual PREPARED FOR: U.S. Army Medical Research and Materiel Command Fort Detrick, Maryland 21702-5012 DISTRIBUTION STATEMENT:  Approved for public release; distribution ...

We examine the state of game theory. Many important questions have been answered, and game theoretic methods are now central to much economic investigation. We suggest areas where further advances are important, and argue that models of learning and of social preferences provide promising routes for improving and widening game theory’s predictive power, while preserving the sucesses of existing...

Background This study investigated the association between socioeconomic status and type 2 diabetes (T2D) prevalence in Scotland 2021 tested null hypothesis that inequalities had not changed since they were last described for 2001–2007. Methods Data from a national population-based database 35-to-84-year-olds mid-year population estimates 2019 stratified by sex fifths of Scottish Index Multiple...

The pH on the frustule of individual cells of the marine centric diatoms Coscinodiscus granii and Coscinodiscus wailesii (Bacillariophyceae) was measured with pH microsensors in culture media with increasing pH values of 8.04, 8.14, and 8.22, respectively. In 85-96% of the C.granii cells the pH on the frustule was up to 0.4 units higher than that of the medium, reaching a maximum pH 8.95. Only ...

Why do computers need emotional intelligence? Science fiction often portrays emotional computers as dangerous and frightening, and as a serious threat to human life. One of the most famous examples is HAL, the supercomputer onboard the spaceship Discovery, in the movie 2001: A Space Odyssey. HAL could express, recognize and respond to human emotion, and generally had strong emotional skills – t...

Results Between 1984 and 2001, it was found that 1285 HIVpositive cases were Saudis averaging 76 new cases per year. The reported HIV-positive person at the end of 2004 was 2005 cases. The rate of annual incidence of HIV-infection in Saudis was ranging 229-505 cases per year on 2001 2009. Between 2001 and 2009 the mean annual incidence of HIV-infection in Saudis was 342 cases per year. The last...

Following the publication of major trials and other studies of hormone replacement therapy, patients in the UK have been advised not to take the drug long-term and to limit short-term use. Response to the new evidence in terms of prescribing in the US has been published recently and we thought it important to assess changes in use in England. Prevalence of use in England increased steadily in t...

Snow cover phenology has exhibited dramatic changes in the past decades. However, distribution and attribution of hemispheric scale snow anomalies remain unclear. Using satellite-retrieved products, ground observations, reanalysis climate variables, this study explored onset date, end duration days over Northern Hemisphere from 2001 to 2020. The latitudinal altitudinal distributions 20-year ave...

background the number of patients with gastric cancer is growing worldwide. in iran (in 2009) of the 74067 new cases of cancer, 6886 were diagnosed as having gastric cancer. this study was conducted to investigate 5-year survival rate for gastric cancer in yazd province, central iran. methods in this descriptive study, the medical records of patients with gastric cancer were collected from the ...

Vagueness is not undecidability, but undecidability does enter into an explanation of why there is vagueness. My theory, called the Undecidability Theory of Vagueness, explains vagueness largely as a result of the fact that we are computationally bound.1 Vagueness is not due to any particularly human weakness, but due to a weakness that any computationally bound agent possesses; even HAL from 2...