Burns range in severity depending on the amount of area they cover on the body and how deeply they penetrate the skin and tissue beneath. Wound healing is an intricate and orchestrated process involving the interactions of various cell components to establish a provisional tissue and then remodel this while forming the mature replacement. Many types of polymers had been used for wound healing t...

Background: Abdominal wound dehiscence (AWD) is a severe postoperative complication associated with high mortality and morbidity. Prolonged hospital stay, high incidence of incisional hernia, and subsequent reoperations underline the severity of this complication. The goal of the underlying study was to evaluate possible risk factors for abdominal wound dehiscence and its management. Methods: T...

Chronic wounds are an important health problem because they are difficult to heal and treatment is often complicated, lengthy and expensive. For a majority of sufferers the most common outcomes are long-term immobility, infection and prolonged hospitalisation. There is therefore an urgent need for effective therapeutics that will enhance ulcer healing and patient quality of life, and will reduc...

In severe appendicitis, the effect of a single intravenous dose of metronidazole (500 mg) was compared with cefoxitin (1 g). The antibiotics were given by random allocation once the diagnosis had been established at operation. In the metronidazole group, 5 out of 48 patients developed a wound infection whilst in hospital compared with 13 out of 48 in the cefoxitin group (P=0-036). However, 57% ...

Background The use of negative-pressure wound therapy (NPWT) for Fournier gangrene management is well documented; however, it is difficult to fixate GranuFoam dressings and maintain an airtight seal over the perineum area. We developed a simple method to facilitate GranuFoam fixation and improve airtight sealing. Methods The Fournier's gangrene severity index (FGSI) score less than 9 was coll...

External fixation combined with colostomy is a traditional management of the pelvic fractures associated with perineal lacerations. However, malunion and dysfunction caused by malreduction and loss of reduction are common. One-stage definitive fixation without soft tissue harassment is requisite for the treatment. The purpose of this study was to assess the outcome of 1-stage definitive fixatio...

Severe weight loss resulting from inadequate nutritional intake along with the hypermetabolism after thermal injury can result in impaired immune function and delayed wound healing. This observational study was conducted on adults admitted between October 2007 and April 2012 with at least 20% total body surface area burn requiring excision who previously tolerated gastric enteral nutrition at c...

conclusions the designed safe irrigator syringe seems to be applicable in wound irrigation and superior to the conventional devices regarding efficacy and user comfort. results all of the interns stated that the new device is quite applicable for wound washing and is easy to handle. nine interns believed that safe irrigator syringe is superior to the conventional devices regarding efficacy and ...

objective(s) wound healing represents a dynamic physiological process influenced by many factors. the aim of the present study was to evaluate the effects of teucrium polium honey on the wound healing and tensile strength in rat. materials and methods thirty-six sprague-dawley rats were randomly divided into four equal (n= 9) treatment and control groups. two full-thickness wounds were made ove...