This work reports a facile sonochemical route in the synthesis of nano particle of deferasirox for the first time. One application of nanotechnology is in improvement of available treatments for various diseases. Deferasirox (ICL670 or Exjade) is a tridentate chelating agent for removing transfusion overload iron in thalassemia patients. In the present work, deferasirox was prepared in nano size...

The objectives in this study were to identify the indicators of occupational stress for academic staff in South African higher education institutions, to analyse the differences between the occupational stress of different demographic groups, and to investigate whether occupational stressors predict ill health and a lack of organisational commitment of academics in higher education institutions...

The purpose of this study was to evaluate the factors influencing work exhaustion and its mediating role on turnover intentions in the context of manufacturing and services sector of Pakistan. The study is based on extensive review of literature and comprehensive statistical analysis (correlation, regression and mediation analysis). The results of this study support the view that work family co...

juvenile hemochromatosis is a rare autosomal recessive disorder that typically occurs in the first to third decades of life. its symptoms are more acute and severe than classic hemochromatosis. we describe a 27-year-old man who was referred to the gastrointestinal clinic with a probable diagnosis of fatty liver and was finally diagnosed as having juvenile hemochromatosis. a review of the scient...

hydroxypyridinone iron chelators are currently the main candidates for development of orally active iron chelating alternatives to desferrioxamine (dfo). in the present study, the relative efficacy and liver toxicity of a bidentate chelator, 2-methyl-3-hydroxypyridin-4-one (mhpo), was studied in iron overloaded rats and compared with those of dfo. for iron overloading, rats received i.p. inject...

This is a prospective study that focused on the dynamics of operating rooms using operational indexes that measure optimization, resistance, overload and utilization of the surgical unit, and also identified the factors most associated with these indexes. A total of 1,908 surgeries were analyzed over a period of two months in 2007. The average rates of utilization, optimization and resistance i...

Hypertrophy is considered one of the major mechanisms of the myocardium for adapting to hemodynamic overload. More muscle mass provides more contractile elements for generating the extra work required by the overload. In pressure overload of aortic valve stenosis, concentric left ventricular hypertrophy (LVH) normalizes wall stress, a key determinant of ejection performance.1 Afterload is often...

| Substantial interest has developed in recent years in building computer systems that support cooperative work among groups without the need for physical proximity. This paper examines some of the di cult data management issues in designing systems for computer-supported cooperative work (CSCW). Speci cally, we consider an example CSCW system to support large-scale team science over the Intern...

| Substantial interest has developed in recent years in building computer systems that support cooperative work among groups without the need for physical proximity. This paper examines some of the diicult data management issues in designing systems for computer-supported cooperative work (CSCW). Speciically, we consider an example CSCW system to support large-scale team science over the Intern...

We evaluate links between climate and simulated river bank erosion for one of the world's largest rivers, the Mekong. We employ a process-based model to reconstruct multidecadal time series of bank erosion at study sites within the Mekong's two main hydrological response zones, defining a new parameter, accumulated excess runoff (AER), pertinent to bank erosion. We employ a hydrological model t...