The present study was performed to examine the relation between the gain of the baroreceptor reflex and the pathogenesis of hypertension in the spontaneously hypertensive rat. Spontaneously hypertensive or Wistar-Kyoto rats underwent either sinoaortic baroreceptor denervation or sham denervation at 28-35 days of age. Four months later these rats were chronically instrumented for measurements of...

Background: Male infertility is considered a major cause of couple as it represents 25- 50 % cases. In addition, non-obstructive azoospermia (NOA) 10% all infertile men.There no definite curable treatment for such cases.
 Aim Work: The purpose this research was to assess the efficacy BM-MSCs and AT-MSCs in treating busulfan-induced wistar rats.
 Materials Methods: were extracted from ...

The development of vitamin K deficiency, vitamin K requirement and warfarin susceptibility were studied in several types of warfarin-resistant .and non-resistant rat. Domesticated HW strain rats needed about 13 times as much vitamin Kl as did Wistar rats to maintain normal blood-clotting function, while HS strain rats were intermediate in this and in their susceptibility to warfarin. The vitami...

Wistar rats were given a diet with 8% sodium chloride to induce hypertension and subsequently sacrificed. Glycine max powder was used reduce atenolol’s side effects during the trial. Thirty divided into five groups tested over eight weeks. Rats’ blood pressure (BP) measured tail-cuff NIBP monitor. Biochemical markers like TG, TC, HDL, LDL, VLDL, alanine transferase, aspartate lipid peroxide (LP...

Spontaneously hypertensive rats (SHR) are widely used as a model of attention deficit hyperactivity disorder (ADHD) as their ADHD-like behaviors are restored by methylphenidate. However, a postnatal neural development in SHR is unknown. We performed whole cell patch clamp recordings from locus coeruleus (LC) neurons in neonatal [postnatal day (P) 3-5], juvenile (P21-28), and adult (P 49-56) SHR...

This study examined whether the calcium antagonist nisoldipine can shift the relations between sodium excretion, papillary blood flow, renal interstitial pressure, and renal perfusion pressure toward lower pressures in spontaneously hypertensive rats. Mean arterial pressure decreased similarly by 9% and 12% in Wistar-Kyoto and spontaneously hypertensive rats after nisoldipine (0.5 microgram/kg ...

This study examined whether the calcium antagonist nisoidipine can shift the relations between sodium excretion, papillary blood flow, renal interstitial pressure, and renal perfusion pressure toward lower pressures in spontaneously hypertensive rats. Mean arterial pressure decreased similarly by 9% and 12% in Wistar-Kyoto and spontaneously hypertensive rats after nisoidipine (0.5 /xg/kg bolus+...

In Indonesia, cruciferous cabbage is known as Ceciwis (Brassica oleracea L. var. capitata f. alba Alef), a vegetable that can be consumed diet from Tegal one of the plants rich in flavonoids and phenol proposed has an antidyslipidemic ac-tivity. The purpose this study to see how affect lipid profile Wistar rats (Rattus norvegicus) fed high-fat diet. Method: Rats divided into seven groups: norma...

Lymphocyte number and weight and their sodium and potassium contents and net passive fluxes were measured in spontaneously hypertensive stroke-prone rats, deoxycorticosterone acetate-treated rats, and two-kidney, one clip renal hypertensive rats. Wistar-Kyoto rats were used as controls for the spontaneously hypertensive stroke-prone rats, and normal intact Sprague-Dawley rats were used as contr...

The value of restenosis after percutaneous coronary intervention (PCI) is recognized worldwide, especially for diabetic patients. Interleukin-1/Toll-like receptor (IL-1/TLR) signaling is involved in innate and adaptive immune responses, but whether and how the IL-1/TLR-induced nuclear factor kappa B (NFκB) pathway plays key roles in intimal formation is unclear. The underlying mechanism of inti...