BACKGROUND The occurrence of basal cell carcinoma within a port-wine stain or nevus flammeus is rare. Sixteen cases of basal cell carcinoma which developed in a port-wine stain or nevus flammeus have been reported. OBJECTIVE The objective was to demonstrate a rare case of basal cell carcinoma occurring in a port-wine stain successfully treated with Mohs micrographic surgery. METHODS This is...

BACKGROUND AND OBJECTIVES Clinical results have demonstrated that dark purple port wine stain (PWS) birthmarks respond favorably to laser induced photothermolysis after the first three to five treatments. Nevertheless, complete blanching is rarely achieved and the lesions stabilize at a red-pink color. In a feasibility study (Part I), we showed that local hypobaric pressure on PWS human skin pr...

port wine stains are benign but cosmetically devasting congenital angiomas. the argon laser is a therapeutic device newly applied to this condition. our program was begun 6 years ago. from the beginning, the study was conceived as a clinical investigation of both the port wine stain and its argon laser therapy. a total of 218 patients with port wine stains have been studied and many aspects of ...

BACKGROUND AND PURPOSE Sturge-Weber syndrome (SWS) is frequently associated with neurologic complications such as seizures, so diagnosing this condition has important implications for patient management. The purpose of this study was to report unusual neuroimaging findings in patients with facial port-wine stain (PWS) and clinically suspected SWS. MATERIALS AND METHODS Cranial MR imaging was ...

Port wine stain (PWS) birthmarks are a congenital and progressive vascular malformation of the dermis, involving capillaries, which occurs in approximately 0.7% of children. The objective of laser surgery for this and similar conditions is to cause selective thermal damage, thrombosis, and, eventually, permanent photocoagulation in the PWS vessels. To achieve this, the radiated laser light is s...

BACKGROUND The prevalence of capillary malformations, also known as port-wine stains (PWS), is 0.3%. Familial segregation can occur. The capillary malformation-arteriovenous malformation (CM-AVM) phenotype is caused by mutations in the RASA1 gene. In PWS familial cases, the inheritance is considered to be autosomal dominant with variable penetrance. OBJECTIVE Investigation of the heredity of ...

BACKGROUND Patients with facial port-wine stains (PWS) often demonstrate oral manifestations of their disorder; however, the spectrum and prevalence of such findings among a cohort of patients with PWS has not been established. As a result, dermatologists and oral health specialists may be uncertain how to counsel their patients with PWS regarding oral hypervascularity, bony oral changes, and o...

BACKGROUND/OBJECTIVES Current laser therapy of port wine stain (PWS) birthmarks with a single laser pulse (SLP) does not produce complete lesion removal in the majority of patients. To improve PWS therapeutic efficacy, we evaluated the performance of an approach based on multiple laser pulses (MLP) to enhance blood vessel photocoagulation. STUDY DESIGN The hamster dorsal window chamber model ...

Port wine stain (PWS) is a congenital, progressive vascular malformation of human skin. Presently, all PWS patients are treated using single cryogen spurt and single laser pulse exposure (SCS-SLP), which does not produce complete lesion blanching in the vast majority of patients. In this study, the feasibility of applying multiple cryogen spurts intermittently with multiple laser pulse exposure...

BACKGROUND So far, pulsed dye lasers have been regarded as the gold standard in the treatment of port-wine stains (PWS). Recently, intense pulsed light (IPL) has been reported to achieve more pronounced fading in some patients. OBJECTIVES To evaluate the efficacy and the side effects of IPL treatment of PWS in a direct comparison to the short-pulsed dye laser (SPDL) and the long-pulsed dye la...