After brief starvation, vertebrates maintain blood glucose by releasing fatty acids from adipose tissue. The fatty acids provide energy for gluconeogenesis in liver and are taken up by muscle, sparing glucose. After prolonged starvation, fat stores are depleted, yet blood glucose can be maintained at levels sufficient to preserve life. Using a new mouse model, we demonstrate that survival after...

Calcium is one of the major mineral nutrients in goat milk. Tryptophan hydroxylase 1 (TPH1) a rate-limiting enzyme catalyzing hydroxylation l-tryptophan into 5-hydroxytryptamine (5-HT, serotonin) essential for maintaining calcium homeostasis. In this study, TPH1 knockout mammary epithelial cells(GMEC) heterozygous clone with no off-target effects were obtained after transfection Cas9/sgRNA expr...

The satellite I DNAs of domestic goat (Capra hircus) and domestic sheep (Ovis aries) have been studied using molecular hybridisation and restriction enzyme analysis. Both satellite DNAs are composed of repeat units of 820 base pairs in length, but their restriction maps, although similar, differ in certain respects. Thus the majority of sheep satellite I repeat units have two EcoRI sites and on...

paratuberculosis (john’s disease) is infectious and chronically progressive granulomatous disease which affects domestic and wild ruminants. the causative agent is mycobacterium avium paratuberculosis (map), a slow growing mycobactin dependent acid-fast bacillus. we investigated the detection and frequency of map in apparently healthy dromedary and bactrian camels by insertion sequence 900 (is9...

BACKGROUND The prevalence of Campylobacter jejuni and Campylobacter coli was determined in goat and goat meat sold at retail outlets in Lubumbashi, Democratic Republic of Congo (DR Congo). METHODOLOGY A total of 644 samples, including 177 goat meat, 86 goat stomachs, 139 ready to eat (RTE) goat skewers, and 242 goat faecal samples were examined for the presence of Campylobacter jejuni and Cam...

BACKGROUND Goat milk production in Shaanxi province is dominant in China, but the product is mainly infant formula and adult milk powder; product homogeneity is serious and has no goat yoghurt with probiotic culture. METHODS The effect of bacteria proportion (1:3:1, 1:2:1, 1:1:1, 2:1:1, 3:1:1) on pH, acidity, and viable counts and sensory evaluation of goat milk fermented by probiotics includ...

the objective of this research was to discriminate four local breeds of goat in central java-indonesia using multivariate analysis. data from eight morphological traits of four goat breeds, namely kejobong goat (jg), etawa grade goat (egg), kacang goat (kg) and jawarandu goat (rg) originated from purbalingga, purworejo, grobogan and pemalang regencies, respectively, were used. one hundred and s...