Background : Although β-arrestin-2 (β-arr2) and CXCR2 have been shown to affect various malignant tumors, their exact roles in lung cancer remain unclear. We investigated expression of β-arr2 and CXCR2 in patients with non-small cell lung cancer (NSCLC) and their correlation with lymph node metastasis and prognosis. Methods : We reviewed medical records of 136 patients with NSCLC who underwent ...

BACKGROUND By using web-based tools in medical education, there are opportunities to innovatively teach important principles from the general competencies of graduate medical education. OBJECTIVES Postulating that faculty transparency in learning from uncertainties in clinical work could help residents to incorporate the principles of practice-based learning and improvement (PBLI) in their pr...

OBJECTIVES The aim of this study was to compare the accuracy, reproducibility, efficacy and effectiveness of measurements obtained using digital models with those obtained using plaster models. MATERIALS AND METHODS A total of 20 digital models were produced by the Ortho Three-dimensional Models (O3DM) Laboratory and their software (O3DM version 2) was used to obtain measurements. Identical p...

PURPOSE To compare the optic disc topography measurements from a digitized laser slit-lamp and a confocal scanning laser ophthalmoscope (SLO). METHODS Ten normal subjects (10 eyes) were recruited. Topographic measurements of the optic disc were performed three times in all eyes using the Retinal Thickness Analyzer (RTA) and the Heidelberg Retina Tomograph II (HRT II), and the mean values dete...

In a 1-day, 1-dose, double-masked, randomised trial, with each of 12 patients acting as his/her own control, atenolol drops 4% (a selective beta1-adrenergic blocker) produced a significantly greater fall in ocular tension measured by applanation than did adrenaline drops 1% (P is less than 0.01 Wilcoxon matched pairs signed ranks test). The mean differences, which favoured atenolol, between the...

BACKGROUND The coexistence of cataract and age related macular degeneration (AMD) is not unusual, especially in the very elderly. The outcome of cataract surgery in these cases depends on the effect of AMD on vision. In this study the authors have compared the outcome of cataract patients with AMD to that of cataract patients with no vision threatening ocular comorbidity, and analysed possible ...

PURPOSE To evaluate the effects of posterior subtenon triamcinolone acetonide injection on refractory diabetic macular edema (DME) after intravitreal bevacizumab (IVB) injection failure. METHODS Patients with DME and central subfield thickness (CST) >300 µm who did not respond to IVB injections were retrospectively included. Specifically, we enrolled patients who were diagnosed with refractor...

AIM The purpose of this study was to compare near visual acuity of dentists without optical aids (VSC) with near visual acuity of those using the Galilean telescope system (VGA2) with magnification of x 2.5, and the distance of 350 mm in simulated clinical conditions. METHODS The study included 46 dentists (visual acuity 1.0 without correction). A visual acuity testing was carried out using a...

BACKGROUND The purpose of this study was to develop a preclerkship elective and assess its effectiveness in supplementing medical students' education. METHODS A group of medical students under the guidance of two faculty advisors developed an elective consisting of six sessions covering a variety of practical aspects of diabetes care/education taught by an interprofessional team. Following th...

DNA barcoding enables precise identification of species from analysis of unique DNA sequence of a target gene. The present study was undertaken to develop barcodes for different species of the genus Dalbergia, an economically important timber plant and is widely distributed in the tropics. Ten Dalbergia species selected from the Western Ghats of India were evaluated using three regions in the p...