Bone scintigraphy or whole-body bone scan is one of the most common diagnostic procedures in nuclear medicine. Since expert physicians evaluate images manually some automated procedure for pathology detection is desired. A robust knowledge based methodology for segmenting body scans into the main skeletal regions is presented. The algorithm is simultaneously applied on anterior and posterior wh...

chronic recurrent multifocal osteomyelitis (crmo) is an inflammatory bone disease usually affecting children. a 9-year old boy presented with recurrent lower extremities pain and discomfort lasting for two years. in every time, symptoms vanished after several weeks. the patient received antibiotics only in one period of bone pain. in other occasions the patient didn’t received any antibiotics. ...

Evaluation of scoliosis is performed traditionally by means of standing posterior-anterior radiographs of the full spine to assess lateral curvature with the Cobb method. In this paper, we present a new automatic algorithm to measure Cobb angle by using nuclear medicine whole body bone scan images. Our algorithm design is based on the fuzzy sets histogram thresholding, anatomical knowledge-base...

The loss of bone and muscle is a major concern for long duration space flight. In December of 1989, we established a collaboration with Russian colleagues to determine the bone and lean tissue changes in cosmonauts before and after flights on the Mir space station lasting 4-14.4 months. Eighteen crew members received a lumbar spine and hip DEXA scan (Hologic 1000W) before and after flight; 17 c...

Mechanical low back pain is a common indication for Nuclear Medicine imaging. Whole-body bone scan is a very sensitive but poorly specific study for the detection of metabolic bone abnormalities. The accurate localisation of metabolically active bone disease is often difficult in 2D imaging but single photon emission computed tomography/computed tomography (SPECT/CT) allows accurate diagnosis a...

twenty-one patients with medullary thyroid carcinoma were studied prospectively with tc-99m (v) dmsa after surgery. pentavalent dmsa scintigram demonstrated abnormal uptake in 13 and equivocal uptake in 6 patients. finally, seven patients with surgical or other imaging documentation were selected for this paper. most of these patients were asymptomatic. six patients had hypercalcitonemia and se...

Twenty-one patients with medullary thyroid carcinoma were studied prospectively with Tc-99m (V) DMSA after surgery. Pentavalent DMSA scintigram demonstrated abnormal uptake in 13 and equivocal uptake in 6 patients. Finally, seven patients with surgical or other imaging documentation were selected for this paper. Most of these patients were asymptomatic. Six patients had hypercalcitonemia ...

Introduction: Medullary thyroid carcinoma (MTC) is a rare thyroid cancer secreting calcitonin (CT) which is the most sensitive and specific tumor marker for MTC. This type of thyroid cancer is able to metastasize to different body areas including regional lymph nodes, lungs, liver and bone. The aim of this study was to assess the sensitivity and specificity of [99mTc-DMSA (V)] whole body ...

PURPOSE The use of SPECT/CT in bone scans has been widespread in recent years, but there are no specific guidelines concerning the optimal acquisition protocol. Two strategies have been proposed: targeted SPECT/CT for equivocal lesions detected on planar images or systematic whole-body SPECT/CT. Our aim was to compare the diagnostic accuracy of the two approaches. METHODS 212 consecutive pati...