the anti-cancer activity of metal ions in the lanthanide group is being considered recently. it has been reported that cerium salts might stimulate the metabolism and therefore, produce anti-cancer effects. however, little is known about the effects of protein-cerium complex in controlling cancer cell growth. the aim of the present study was to elucidate the possible pathways for the cytotoxic ...

objective: poverty alleviation is an essential step to achieve economic development. this is why identification exercise is so crucial. traditionally, different aspects of insecurities have not be taken into poverty measurement. many types of insecurities have adverse impacts on household welfare. identifying vulnerability of household can serve identification of the poor households. methodolog...

a signed graph (marked graph) is an ordered pair $s=(g,sigma)$$(s=(g,mu))$, where $g=(v,e)$ is a graph called the underlyinggraph of $s$ and $sigma:erightarrow{+,-}$$(mu:vrightarrow{+,-})$ is a function. for a graph $g$, $v(g),e(g)$ and $c(g)$ denote its vertex set, edge set and cut-vertexset, respectively. the lict graph $l_{c}(g)$ of a graph $g=(v,e)$is defined as the graph having vertex set ...

objective: verotoxin is a member of shiga toxin family. this family contains ab protein toxins with an enzymatic (a) and a binding (b) compartment. cells that have receptor (gb3) are sensitive to cytotoxic effects of toxin. it has been shown that various tumor cells have gb3 receptor and are selectively sensitive to apoptotic effect of verotoxin. studies on tumor cell lines and laboratory anima...

in this paper, the optimum shape of tailor-welded blanks (twb) is investigated. the optimization is performed for two different case studies. the first example is deep drawing of a twb with dissimilar materials and uniform thicknesses and the next example is deep drawing of a twb with similar materials and non-uniform thicknesses. the effect of blank optimization on the weld line movement is in...

objective: today, special attention is paid to the use of zirconium dioxide nanoparticle (nano-zro2), a neutral bioceramic metal, particularly for drug and gene delivery in medicine. however, there are some reports implying that use of nano-zro2 is associated with cytotoxic effects like inhibiting the cell proliferation, dna damage and apoptosis. in the present study, we examined whether nano-z...

with the growth in customers’ demand diversification, mixed-model u-lines (mmul) have acquired increasing importance in the area of assembly systems. there are generally two different approaches in the literature for balancing such systems. some researchers believe that since the types of models can be very diverse, a balancing approach without simultaneously sequencing of models will not yield...

background; work-related musculoskeletal disorders (wmsds) may involve all parts of the body, and have been a worldwide problem. employed women are two to five times more likely to report such problems, and assembly lines suspected to induce more wmsds because of high rate of repetitive motions. methods;the aim of this study to determine the prevalence of wmsds in women workers of an automobile...

Despite intense scrutiny, cancer remains a formidable disease with limited therapeutic options, especially in the context of metastatic disease (Fisher, 2005). Metastasis, formation of secondary tumors is a turning point in tumourogenesis and consists of complex series of parallel, yet intertwined events (Bogenrieder, 2003). Several molecules and signals in the host system especially in the tum...