OBJECTIVE The objectives were to investigate the characteristics associated with frequent self-weighing and the relationship between self-weighing and weight loss maintenance. RESEARCH METHODS AND PROCEDURES Participants (n = 3003) were members of the National Weight Control Registry (NWCR) who had lost >or=30 lbs, kept it off for >or=1 year, and had been administered the self-weighing freque...

OBJECTIVE To determine the effect of partial Kangaroo Mother Care (KMC) on growth rates and duration of hospital stay of Low Birth Weight (LBW) infants. DESIGN Unblinded, randomised clinical controlled trial. SETTING Kenyatta National Hospital, Nairobi, Kenya. SUBJECTS Over a nine month period, consecutive recruitment of eligible LBW infants weighing 1000 g to 1750 g was done until a samp...

BACKGROUND The regional Mediterranean Diet has been associated with lower risk of disease. OBJECTIVE We tested the health effects of the New Nordic Diet (NND), which is a gastronomically driven regional, organic, and environmentally friendly diet, in a carefully controlled but free-living setting. DESIGN A total of 181 centrally obese men and women, with a mean (range) age of 42 y (20-66 y)...

BACKGROUND Whether testosterone treatment has benefits on body composition over and above caloric restriction in men is unknown. We hypothesised that testosterone treatment augments diet-induced loss of fat mass and prevents loss of muscle mass. METHODS We conducted a randomised double-blind, parallel, placebo controlled trial at a tertiary referral centre. A total of 100 obese men (body mass...

INTRODUCTION Prevention of lymphocyte apoptosis by caspase inhibition has been proposed as a novel treatment approach in sepsis. However, it has not been clearly demonstrated that caspase inhibitors improve survival in sepsis models when dosed post-insult. Also, there are concerns that caspase inhibitors might suppress the immune response. Here we characterize VX-166, a broad caspase inhibitor,...

BACKGROUND In diagnosis and treatment of obesity, body composition analysis including percent body fat (%BF) is useful in the clinical setting. Because bioelectrical impedance analysis (BIA) could be used quickly, easily and was non-invasive in clinical setting, the purpose of the present study was to evaluate the usefulness of multi-frequency BIA with eight-point tactile electrodes (MF-BIA8; I...