We present a case of subglottic stenosis (SGS) in a young patient with positive ANCA but a wrong diagnosis of Wegener granulomatosis (WG). Instead, she was diagnosed as having laryngopharyngeal reflux (LPR). Pitfalls of ANCA testing in this scenario, the route to diagnosis of LPR and the contribution of this entity to subglottic stenosis (SGS) in WG are discussed. Caution when interpreting ANCA...

1 Rosen MJ. Dr. Friedrich Wegener, the ACCP, and history. Chest 2007; 132:739–741 2 Mitcham S. Why Hitler? Westport, CT: Praeger Publishing, 1996 3 Woywodt A, Haubitz M, Haller H, et al. Wegener’s granulomatosis. Lancet 2006; 367:1362–1366 4 Woywodt A, Matteson EL. Wegener’s granulomatosis: probing the untold past of the man behind the eponym. Rheumatology (Oxford) 2006; 45:1303–1306 5 Strous R...

Wegener’s granulomatosis, first described by Friedrich Wegener in 1936, is a systemic vasculitis that characteristically causes necrotizing granulomas of the respiratory tract and necrotizing cresentic glomerulonephritis. This article describes the history and modern treatment of the disease in conjunction with a clinical case.

We report on a case of Wegener granulomatosis in the pterygopalatine fossa that was associated with trigeminal neuropathy. MR and CT examinations were useful in depicting the extent of the lesion and suggesting a perineural spread. Diagnosis was confirmed with positive serum assay findings for the presence of cytoplasmic antineutrophil cytoplasm antibody.

Granulomatosis with polyangiitis (GPA, formerly Wegener granulomatosis) is a vasculitis with various organ involvement. There have been a few cases of CNS stroke and rare cases of lateral medullary infarction (LMI) as a manifestation of GPA. Also there have been reports of sinuses, nose and laryngeal masses mistakenly referred as carcinomas and subsequently GPA was diagnosed in their pathologic...

Vasculitides that affect the lung represent a diverse group of diseases with various systemic clinical manifestations, and include microscopic polyangiitis (MPA), granulomatosis with polyangiitis (GPA, formerly Wegener granulomatosis), Churg-Strauss syndrome (CSS), and anti-glomerular basement membrane (anti-GBM) disease (Goodpasture syndrome). The etiologies of these diseases remain largely un...

La granulomatosis de Wegener o con Poliangitis (GPA) es una enfermedad caracterizada por inflamación y necrosis las paredes los vasos sanguíneos. Es etiología desconocida, baja prevalencia alta agresividad. Esta puede comprometer tejidos bucales causando agrandamiento e del tejido gingival. Se reporta el caso un paciente género masculino que manifiesta aumento volumen la encía asociado al ...